Abstract
Reactions of 2-(2-aminoethoxy)ethanol with mixtures of an aromatic aldehyde and aroylpyruvic acid methyl ester have afforded 5-aryl-4-aroyl-3-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-3-pyrrolin-2-ones. Antihypoxic activity of the synthesized compounds has been studied.
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Original Russian Text © V.L. Gein, S.N. Rogachev, A.A. Bobyleva, D.Yu. Apushkin, G.A. Veikhman, O.E. Nasakin, 2015, published in Zhurnal Obshchei Khimii, 2015, Vol. 85, No. 11, pp. 1826–1829.
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Gein, V.L., Rogachev, S.N., Bobyleva, A.A. et al. Synthesis and antihypoxic activity of 5-aryl-4-aroyl-3-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-3-pyrrolin-2-ones. Russ J Gen Chem 85, 2568–2570 (2015). https://doi.org/10.1134/S1070363215110109
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DOI: https://doi.org/10.1134/S1070363215110109