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Synthesis, spectroscopic, and molar conductance characterization of selenium(IV) vitamin B6 complex as prospective antioxidant agent

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Abstract

Selenium(IV) complex of vitamin B6 has been prepared using Se(IV) tetrachloride and characterized using spectroscopy (IR, UV-Vis, H NMR), molar conductance measurements, thermal analysis (DTA and TGA) and SEM imaging. Micro-analytical and spectral data show that the formed selenium(IV) complex is 1 : 2 (Se : vitamin B6) molar ratio. Vitamin B6 and its selenium complex were screened for in vitro antioxidant activity. The complex exhibited stronger antioxidant activity in 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical assay compared to the free vitamin B6 ligand.

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Correspondence to Moamen S. Refat.

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Refat, M.S., Kobeasy, M.I. & EL-Shazly, M.A. Synthesis, spectroscopic, and molar conductance characterization of selenium(IV) vitamin B6 complex as prospective antioxidant agent. Russ J Gen Chem 84, 1411–1416 (2014). https://doi.org/10.1134/S1070363214070299

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  • DOI: https://doi.org/10.1134/S1070363214070299

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