Abstract
Selenium(IV) complex of vitamin B6 has been prepared using Se(IV) tetrachloride and characterized using spectroscopy (IR, UV-Vis, H NMR), molar conductance measurements, thermal analysis (DTA and TGA) and SEM imaging. Micro-analytical and spectral data show that the formed selenium(IV) complex is 1 : 2 (Se : vitamin B6) molar ratio. Vitamin B6 and its selenium complex were screened for in vitro antioxidant activity. The complex exhibited stronger antioxidant activity in 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical assay compared to the free vitamin B6 ligand.
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Yang, K.W., Wang, L.F., Wu, J., and Yang, Z.Y., J. Inorg. Biochem., 1993, vol. 52, p. 151.
Metzler, D.E., and Snell, E.E., J. Am. Chem. Soc., 1955, vol. 77, p. 2431.
Matushima, Y., and Martell, A.E., J. Am. Chem. Soc., 1967, vol. 89, p. 1322.
Lapper, R.D., Manisch, H.H., and Smith, I.C.P., Can. J. Chem., 1975, vol. 53, p. 2406.
Hanic, F., Acta Crystallogr., 1966, vol. 21, p. 332.
Back, D.F., de-Oliveira, G.M., and Lang, E.S., J. Inorg. Biochem., 2006, vol. 100, p. 1698.
Neelakantan, M.A., Sundaram, M., Thalamuthu, S., and Nair, M.S., J. Coord. Chem., 2010, vol. 63, p. 1969.
Chamayou, A.C., Neelakantan, M.A., Thalamuthu, S., and Janiak, C., Inorg. Chim. Acta, 2011, vol. 365, p. 447.
Acquaye, J.H.K.A. and Richardson, M.F., Inorg. Chim. Acta, 1992, vol. 201, p. 101.
Denslow, S.A., Walls, A.A., and M.E. Daub, Physiological and Molecular Plant Pathology, 2005, vol. 66, p. 244.
Gliszczynska-swiglo, A., and Szmusiak, H., Pol. J. Food Nutr. Sci., 2007, vol. 57, p. 163.
Endo, N., Nishiyama, K., Otsuka, A., Kanouchi, H., Taga, M., and Oka, T., British J. Nutrition, 2006, vol. 95, p. 1088.
Choi, E., and Cho, Y., Nutrition Research and Practice, 2009, vol. 3, p. 208.
Sabir, S.M., Salman, S.M., Rocha, J.B.T., Enviromental Toxicology and Pharmacology, 2012, vol. 43, p. 446.
Bordoni, A., Cabrini, L., Marchetti, M., Danesi, F., Bochicchio, D., Biagi, P.L., and Maranesi, M., Ann. Nutr. Metab., 2006, vol. 50, p. 305.
Vivane, P.S. Danubia, B.S., Marcio, W.F., Nogueira, C.W., Rocha, J.B.T., and Gilso, Z., Chem. Biol. Inter., 2009, vol. 177, p. 28.
Biois, M.S., Nature, 2002, vol. 26, p. 1199.
Geary, W.J., Coord. Chem. Rev., 1971, vol. 7, p. 81.
Refat, M.S., Spectrochim Acta A, 2007, vol. 68, p. 1393.
Acquaye, H.K.A., Master Thesis, Brock University, St Catherine’s, Ontario, Canada, 1982.
Tabassum, S., Siddiqi, K.S., Khan, N.H., Kureshy, R.I., and Zaid, S.A.A., Indian J. Chem., 1987, vol. 26, p. 523.
Nakamoto, K., Infrared Spectra of Inorganic and Coordination Compounds, 2nd ed., New York: Wiley-Interscience, 1970.
Agarwal, R.K., Garg, R.K., and Sindhu, S.K., J. Iranian Chem. Soc., 2005, vol. 2(3), p. 203.
Franklin, T.A., and Richardson, M.F., Inorg. Chim. Acta, 1980, vol. 46, p. 191.
Lever, A.B.P., Mantiovani, E., and Ramaswamy, B.S., Can. J. Chem., 1971, vol. 49, p. 1957.
Singh, H.L., and Varshney, A.K., Bioinorg. Chem. Appl., 2006, doi:10.1155/BCA/2006/23245.
Radhakrishnan, P.S., and Indrasenan, P., Indian J. Chem., 1989, vol. 28, p. 234.
Cullity, B.D., Elements of X-ray Diffraction, Addison-Wesley, Mass, 1978.
Nantitanon, W., and Okonogi, S., Durg Discoveries and Therapeutics, 2012, vol. 6, p. 38.
Shimada, K., Fujikama, K., Yahara, K., and Nakamura, T., J. Agricultural and Food Chemistry, 1992, vol. 40, p. 945.
Pahlavanzadeh, F., Bidadkosh, A., Derakhshanfar, A., Rastegar, A.M., and Rushanzamir, M., Comparative Clinical Pathology, 2013, vol. 22, p. 637.
Stocker, P. Lesgards, J., Vidal, N., Chalier, F., and Prost, M., Biochimica et Biophysica Acta, 2003, vol. 1621, p. 1.
Schafer, F.O., and Buettner, G.R., Free Radic. Biol. Med., 2001, vol. 30, p. 1191.
Battin, E.E., and Brumaghim, J.L., Cell Biochem. Biophys, 2009, vol. 55, p. 1.
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Refat, M.S., Kobeasy, M.I. & EL-Shazly, M.A. Synthesis, spectroscopic, and molar conductance characterization of selenium(IV) vitamin B6 complex as prospective antioxidant agent. Russ J Gen Chem 84, 1411–1416 (2014). https://doi.org/10.1134/S1070363214070299
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DOI: https://doi.org/10.1134/S1070363214070299