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Thermoresponsive hydrogels with ultrasound-controlled properties

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Abstract

Possibility of creation of materials with transport properties operated by ultrasound on the basis of thermosensitive hydrogels modified by a solid phase of inorganic compounds is shown. The kinetic model of drug release from the hydrogel matrix, which allows to optimize the parameters of ultrasound exposure is proposed. Various options of devices with operated ultrasound an outlet of medicinal substance are offered.

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Authors and Affiliations

  1. Lomonosov Moscow State University, Moscow, 119991, Russia

    A. L. Nikolaev, V. L. Zelenko, A. V. Gopin & V. E. Bozhevol’nov

  2. Felitsata Kholding, Limited Liability Company, ul. Khachaturyana 7, Moscow, 127562, Russia

    D. S. Chicherin

Authors
  1. A. L. Nikolaev
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  2. V. L. Zelenko
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  3. D. S. Chicherin
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  4. A. V. Gopin
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  5. V. E. Bozhevol’nov
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Correspondence to A. L. Nikolaev.

Additional information

Original Russian Text © A.L. Nikolaev, V.L. Zelenko, D.S. Chicherin, A.V. Gopin, V.E. Bozhevol’nov, 2012, published in Rossiiskii Khimicheskii Zhurnal, 2012, Vol. 56, Nos. 5–6, pp. 52–64.

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Nikolaev, A.L., Zelenko, V.L., Chicherin, D.S. et al. Thermoresponsive hydrogels with ultrasound-controlled properties. Russ J Gen Chem 84, 1018–1030 (2014). https://doi.org/10.1134/S1070363214050399

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  • DOI: https://doi.org/10.1134/S1070363214050399

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