Skip to main content
SpringerLink
Log in

Electrochemically controlled methods for removal of endo- and exotoxicants from biological media

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

The electrochemical model of the system of electroconductive hemosorbent/biological medium was proposed to develop electro-chemically controlled medical detoxification technologies for treat-ment of diseases of certain etiology. It was obtained that the destruc-tion of blood cells as a result of a contact blood with hemosorbents is caused of hemosorbent potential. The potential region of hemosor-bent corresponding of hemocompatibility was determined. Hemo-compatible composite material based on activated carbon covered polypyrrole were synthesized. Certain electrochemical medical tech-nologies for selective removing of endo- and exotoxicants and dam-aged blood cells from biological media of organism were developed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Tarasevich, M.R., Elektrokhimiya uglerodnykh materialov (Electrochemistry of Carbon Materials), Moscow: Nauka, 1984.

    Google Scholar 

  2. Marsh, H. and Rodrigues-Reinoso, F., Activated Carbon, Oxford: Elsevier Ltd., 2006.

    Google Scholar 

  3. Bansal, R.C. and Goyal, M., Activated Carbon Adsorption, Boca Raton, FL: CRC Press, 2005.

    Book  Google Scholar 

  4. Shannon, M.A., Bohn, P.W., Elimelech, M., et al., Nature, 2008, vol. 452, no. 7185, pp. 301–310.

    Article  CAS  Google Scholar 

  5. Qu, J., J. Environ. Sci., 2008, vol. 20, no. 1, pp. 1–13.

    Article  CAS  Google Scholar 

  6. Tarasevich, M.R., Gol’din, M.M., Luzhnikov, E.A., and Bogdanovskaya, V.A., Itogi Nauki i Tekhn. VINITI, Ser. Elektrokhimiya, 1990, vol. 31, pp. 127–150.

    CAS  Google Scholar 

  7. Grimm, J., Bessarabov, D., and Sanderson, R., Desalination, 1998, vol. 115, no. 3, pp. 285–294.

    Article  CAS  Google Scholar 

  8. Bullock, T.H., Annu. Rev. Physiol., 1951, vol. 13, pp. 261–280.

    Article  CAS  Google Scholar 

  9. Bezanilla, F., Nat. Rev. Mol. Cell Biol., 2008, vol. 9, no. 4, pp. 323–332.

    Article  CAS  Google Scholar 

  10. Gadsby, D.C., Nat. Rev. Mol. Cell Biol., 2009, vol. 10, no. 5, pp. 344–352.

    Article  CAS  Google Scholar 

  11. Franco, R., Bortner, C.D., and Cidlowski, J.A., J. Membr. Biol., 2006, vol. 209, no. 1, pp. 43–58.

    Article  CAS  Google Scholar 

  12. Nordenstrom, B., Biologically Closed Electric Circuit, Uitgever: Nordic Medical Publications, 1983.

    Google Scholar 

  13. Gong, K., Dong, Y., Xiong, S., et al., Biosens. Bioelectron., 2004, vol. 20, no. 2, pp. 253–259.

    Article  CAS  Google Scholar 

  14. Ozkan, S., Uslu, B., Aboul-Enein, H., Crit. Rev. Anal. Chem., 2003, vol. 33, no. 3, pp. 155–181.

    Article  Google Scholar 

  15. Wang, Y., Xu, H., Zhang, J., and Li, G., Sensors, 2008, vol. 8, no. 4, pp. 2043–2081.

    Article  CAS  Google Scholar 

  16. Lambrechts, M. and Sansen, W., Biosensors: Micro-electrochemical Devices, Bristol: Institute of Physics Publishing, 1992.

    Google Scholar 

  17. Schuhmann, W., Lammert, R., Hämmerle, M., and Schmidt, H.L., Biosens. Bioelectron., 1991, vol. 6, no. 8, pp. 689–697.

    Article  CAS  Google Scholar 

  18. Lowry, J.P., Griffin, K., McHugh, S.B., et al., Neuroimage, 2010, vol. 52, no. 2, pp. 549–555.

    Article  Google Scholar 

  19. Atkinson, M.J., Thomas, F.I.M., Larson, N., et al., Deep Sea Research Part I: Oceanographic Research Papers, 1995, vol. 42, no. 5, pp. 761–771.

    Article  CAS  Google Scholar 

  20. Heller, A. and Feldman, B., Chem. Rev., 2008, vol. 108, no. 7, pp. 2482–2505.

    Article  CAS  Google Scholar 

  21. Gol’din, M.M., Luzhnikov, E.A., Evseev, A.K., et al., Aktual’nye voprosy ekstrakorporal’noi terapii (Topical Problems of Extracorporeal Therapy), Moscow, 2007, pp. 129–130.

    Google Scholar 

  22. Gol’din, Mikhail M., Blanchard, G.J., Volkov, A.G., et al., ECS Trans., 2008, vol. 11, no. 20, pp. 19–28.

    Article  Google Scholar 

  23. Gol’din, M.M., Blanchard, G.J., Evseev A.K., et al., 212 Meeting of the Electrochemical Society, Washington, 2007, Abs. 0815.

    Google Scholar 

  24. Gol’din, M.M., Volkov, A.G., Khubutiya, M.Sh., et al., ECS Trans., 2008, vol. 11, no. 21, pp. 39–49.

    Article  Google Scholar 

  25. Khubutiya, M.Sh., Krylov, V.V., Gol’din, M.M., et al., Giperbaricheskaya Fiziologiya i Meditsina, 2009, no. 4, pp. 1–12.

    Google Scholar 

  26. Khubutiya, M.Sh., Gol’din, M.M., Romasenko, M., et al., ECS Trans., 2010, vol. 25, no. 19, pp. 63–71.

    Article  CAS  Google Scholar 

  27. Khubutiya, M.Sh., Evseev, A.K., Kolesnikov, V.A., et al., Russ. J. Electrochem., 2010, vol. 46, no. 5, p. 537.

    Article  CAS  Google Scholar 

  28. Khubutiya, M.Sh., Gol’din, M.M., Evseev, A.K., et al., ECS Trans., 2011, vol. 35, no. 35, pp. 45–50.

    Article  CAS  Google Scholar 

  29. Khubutiya, M.Sh., Pinchuk, A.V., Aleksandrova, I.V., et al., Transplantologiya, 2011, nos. 2–3, pp. 29–33.

    Google Scholar 

  30. Lopukhin, Yu.M. and Molodenkov, M.N., Gemosorbtsiya (Hemosorption), Moscow: Meditsina, 1985.

    Google Scholar 

  31. Nikolaev, V.G., Metod gemokarboperfuzii v eksperimente i klinike (Hemocarboperfusion Method in Experimental and Clinical Conditions), Kiev: Naukova Dumka, 1984.

    Google Scholar 

  32. Chang, T.M., Iskustvennye kletki (Artificial Cells), Kiev: Naukova Dumka, 1979.

    Google Scholar 

  33. Lopatkin, N.A. and Lopukhin, Yu.M., Efferentnye metody v meditsine (Efferent Methods in Medicine), Moscow: Meditsina, 1989.

    Google Scholar 

  34. Chang, T.M.S., Can. J. Physiol. Pharmacol., 1969, vol. 47, no. 12, pp. 1043–1045.

    Article  CAS  Google Scholar 

  35. Luzhnikov, E.A., Gol’din, M.M., and Strakhova, N.M., Farmatsiya, 1983, no. 1, pp. 40–43.

    Google Scholar 

  36. Kharamonenko, S.S. and Rakityanskaya, A.A., Elektroforez kletok krovi v norme i patologii (Blood Cell Electrophoresis in Normal and Pathological Conditions), Minsk: Belarus’, 1974.

    Google Scholar 

  37. Gol’din, M.M., Volkov, A.G., Goldfarb, Yu.S., and Gol’din, Mikhail M., J. Electrochem. Soc., 2006, vol. 153, no. 8, pp. J91–J99.

    Article  Google Scholar 

  38. Frumkin, A.N., Izbrannye trudy: Elektrodnye protsessy (Selected Works: Electrode Processes), Moscow: Nauka, 1987.

    Google Scholar 

  39. Surovikin, V.F., P’yanova, L.G., Luzyanina, L.S., and Dolgikh, V.T., Efferentnaya Terapiya, 2008, vol. 14, nos. 1–2, pp. 4–8.

    Google Scholar 

  40. Surovikin, V.F., Surovikin, Yu.V., and Tsekhanovich, M.S., Ros. Khim. Zh. (Zh. Ros. Khim. Ob-va im. D.I. Mendeleeva), 2007, vol. LI, no. 4. pp. 111–118.

    Google Scholar 

  41. Luzhnikov, E.A., Gol’din, M.M., and Suslova, I.M., Farmatsiya, 1980, no 3, pp. 65–66.

    Google Scholar 

  42. Gol’din, M.M. and Luzhnikov, E.A., Elektrokhim., 1979, vol. 4, no. 9, p. 1419.

    Google Scholar 

  43. Gol’din, M.M., Luzhnikov, E.A., and Suslova, I.M., Elektrokhim., 1980, vol. 16, no. 11, pp. 1667–1669.

    Google Scholar 

  44. Boehm, H.P., Advances in Catalysis, Eley, D.D, Pines, H., and Weisz, P.B., Eds., Academic Press, 1966, pp. 179–274.

  45. Borover, G.Yu., Gol’din, M.M., Shkol’nikov, E.I., et al., Elektrokhim., 1989, vol. 25, no. 5, pp 565–569.

    CAS  Google Scholar 

  46. Bogdanovskaya, V.A., Tarasevich, M.R., and Gol’din, M.M., Itogi Nauki i Tekhniki VINITI, Ser. Elektrokhimiya, vol. 31, pp. 151–166.

  47. Vol’fkovich, Yu.M., Bagotskii, V.S., Sosenkin, V.E., and Shkol’nikov, E.I., Elektrokhim., 1980, vol. 16, no. 11, pp. 1620–1652.

    Google Scholar 

  48. Raicu, V. and Popes, A., Integrated Molecular and Cellular Biophysics, Springer, 2008.

    Book  Google Scholar 

  49. Feng, B., Su, Y., Song, J., and Kong, K., J. Mater. Sci. Lett., 2001, vol. 20, no. 4, pp. 293–294.

    Article  CAS  Google Scholar 

  50. Sadki, S., Schottland, P., Brodie, N., and Sabouraud, G., Chem. Soc. Rev., 2000, vol. 29, pp. 283–293.

    Article  Google Scholar 

  51. Nishizawa, M., Nozaki, H., Kaji, H., et al., Biomaterials, 2007, vol. 28, no. 8, pp. 1480–1485.

    Article  CAS  Google Scholar 

  52. Jiang, X., Marois, Y., Traore, A., et al., Tissue Engineering, 2002, vol. 8, no. 4, pp. 635–647.

    Article  CAS  Google Scholar 

  53. George, P.M., Lyckman, A.W., LaVan, D.A., et al., Biomaterials, 2005, vol. 26, no. 17, pp. 3511–3519.

    Article  CAS  Google Scholar 

  54. Epstein, A.J. and MacDiarmid, A.G., Macromol. Chem., Macromol. Symp., 1991, vol. 51, no. 1, pp. 217–234.

    Article  CAS  Google Scholar 

  55. Goddard, J.M. and Hotchkiss, J.H., Prog. Polym. Sci., 2007, vol. 32, pp. 698–725.

    Article  CAS  Google Scholar 

  56. Urman, M.G., Travma zhivota (Abdominal Trauma), Perm’: IPK Zvezda, 2003.

    Google Scholar 

  57. Dement’eva, I.I., Morozov, Yu.A., and Charnaya, M.A., Kardiologiya i Serdechno-Sosudistaya Khirurgiya, 2008, no. 6, pp. 60–63.

    Google Scholar 

  58. Lopukhin, Yu.M., Molodenkov, M.N., and Shurkalin, B.K., Gemosorbtsiya, Sb. Trudov II MOLGMI im. N.I. Pirogova: (Hemosorption, Collection of Works of N.I. Pirogov Russian National Research Medical University), 1977, pp. 64–69.

    Google Scholar 

  59. Hamburger, J., Presse méd., 1960, vol. 68, pp. 279–281.

    CAS  Google Scholar 

  60. Pearson, R.G., J. Chemical Education, 1968, vol. 45, pp. 581–587.

    Article  CAS  Google Scholar 

  61. Pearson, R.G., J. Chemical Education, 1968, vol. 45, pp. 643–648.

    Article  CAS  Google Scholar 

  62. Rodríguez, F.J., Gutiérrez, S., Ibanez, J.G., et al., Environmental Science and Technology, 2000, vol. 34, no. 10, pp. 2018–2023.

    Article  Google Scholar 

  63. Khubutiya, M.Sh., Gol’din, M.M., Stepanov, A.A., et al., Carbon, 2012, vol. 50, pp. 1146–1151.

    Article  CAS  Google Scholar 

  64. Khubutiya, M.Sh., Tsivadze, A.Yu., Garaeva, G.R., et al., Makrogeterotsikl., 2012, vol. 5, nos. 4–5, pp. 321–326.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. N.V. Sklifosovsky Research Institute of Emergency Medicine, B. Sukharevskaya pl. 3, Moscow, 129090, Russia

    M. Sh. Khubutiya, M. M. Gol’din, G. R. Garaeva & A. A. Stepanov

  2. A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 119991, Russia

    A. Yu. Tsivadze & V. N. Andreev

  3. Liberty University, 1971 University Blvd, Lynchburg, VA, 95653, USA

    Mikh. M. Gol’din

Authors
  1. M. Sh. Khubutiya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Yu. Tsivadze
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. M. Gol’din
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. V. N. Andreev
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. R. Garaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. A. Stepanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Mikh. M. Gol’din
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. M. Gol’din.

Additional information

Original Russian Text © M.Sh. Khubutiya, A.Yu. Tsivadze, M.M. Gol’din, V.N. Andreev, G.R. Garaeva, A.A. Stepanov, Mikh.M. Gol’din, 2012, published in Rossiiskii Khimicheskii Zhurnal, 2012, Vol. 56, Nos. 5–6, pp. 30–42.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Khubutiya, M.S., Tsivadze, A.Y., Gol’din, M.M. et al. Electrochemically controlled methods for removal of endo- and exotoxicants from biological media. Russ J Gen Chem 84, 998–1009 (2014). https://doi.org/10.1134/S1070363214050375

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363214050375

Keywords

Search

Navigation