Abstract
N-Alkylation of primary and secondary amines with monochloroalkyl-gem-dichlorocyclopropanes under conditions of thermal and microwave heating results in the corresponding amino-gem-dichlorocyclopropanes. With microwave irradiation heating, the reaction time has been decreased to 1 h, the yields of the amines containing gem-dichlorocyclopropane moiety being the same. Formation of the bicyclic amine in reaction of cis-2,3-dichloromethyl-gem-dichlorocyclopropane with primary amines under conditions of phasetransfer catalysis has been studied.
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Original Russian Text © E.K. Aminova, A.N. Kazakova, N.N. Mikhailova, S.S. Zlotskii, 2014, published in Zhurnal Obshchei Khimii, 2014, Vol. 84, No. 1, pp. 20–23.
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Aminova, E.K., Kazakova, A.N., Mikhailova, N.N. et al. Reactions of chloroalkyl-gem-dichlorocyclopropanes with amines. Russ J Gen Chem 84, 18–21 (2014). https://doi.org/10.1134/S1070363214010058
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DOI: https://doi.org/10.1134/S1070363214010058