Russian Journal of General Chemistry

, Volume 83, Issue 10, pp 1869–1873 | Cite as

Synthesis and studies of structure and biological properties of D-homoanalogs of steroid estrogens

  • S. N. Morozkina
  • A. F. Fidarov
  • A. S. Mushtukov
  • S. I. Selivanov
  • G. L. Starova
  • A. G. Shawa


In order to estimate the potential of steroid estrogens modification, three D-homoanalogs of estrogens have been prepared; their structures and biological properties have been studied. The expansion of D-ring in such compounds has lead to strong decrease if the uterotropic action, however, the unfavorable hypertriglyceridemic effect has been retained. The latter has been eliminated by combined action of the studied steroids and ursolic acid; therewith the hypocholesterolemic activity has been retained.


Ursolic Acid Ultrasonic Irradiation Steroid Estrogen Sodium Hydrogen Carbonate Triethylsilane 
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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • S. N. Morozkina
    • 1
  • A. F. Fidarov
    • 1
  • A. S. Mushtukov
    • 1
  • S. I. Selivanov
    • 1
  • G. L. Starova
    • 1
  • A. G. Shawa
    • 1
  1. 1.St. Petersburg State UniversitySt. PetersburgRussia

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