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Russian Journal of General Chemistry

, Volume 83, Issue 6, pp 1077–1080 | Cite as

Kinetics and mechanism of transaldimination of amino acids and aromatic amines with pyridoxal

  • F. V. Pishchugin
  • I. T. Tuleberdiev
Article

Abstract

Kinetics and mechanism of transaldimination of amino acids and aromatic amines with pyridoxal have been studied by means of UV spectroscopy and polarimetry. It has been shown that aminal intermediates are formed in reaction of the Schiff’s bases with p-aminobenzoic acid and β-alanine. The structure of aminal and Schiff’s base is determined by the spatial arrangement of the amino acid and aromatic fragments with respect to the pyridine ring plane. The presence of OH and CH2-OH groups in the o-positions in pyridoxal structure turns amino groups by 90° with respect to the pyridine ring. The scheme of Schiff’s bases transaldimination by amino acids and biological amines has been developed according to stereospecific, energy, and geometric factors.

Keywords

Pyridoxal Aromatic Amine Aminobenzoic Acid Amino Alcohol Amino Acid Fragment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  1. 1.Institute of Chemistry and Chemical TechnologyKyrgyz Republic National Academy of SciencesBishkekKyrgyzstan

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