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The features of the synthesis and chemical behavior of some β-cyclodextrin silyl derivatives

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Abstract

Conditions are found for the regioselective silylation of the β-cyclodextrin primary hydroxy groups by diphenylmethylsilyl chloride and trimethylsilyl chloride. It is shown that the position of silyl substituents at the primary or secondary hydroxyl can be determined using 29Si NMR spectroscopy. In the case of acetic and phosphorous acid chlorides, the subsequent functionalization of the secondary hydroxyls occurs with a significant removal of the protective silyl groups.

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Authors and Affiliations

  1. Department of Chemistry, Moscow State Pedagogical University, Nesvizhskii per. 3, Moscow, 119021, Russia

    G. I. Kurochkina, A. V. Edunov, A. G. Astakhova, M. K. Grachev, I. I. Levina & E. E. Nifant’ev

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  1. G. I. Kurochkina
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  2. A. V. Edunov
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  3. A. G. Astakhova
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  4. M. K. Grachev
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  5. I. I. Levina
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  6. E. E. Nifant’ev
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Correspondence to G. I. Kurochkina.

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Original Russian Text © G.I. Kurochkina, A.V. Edunov, A.G. Astakhova, M.K. Grachev, I.I. Levina, E.E. Nifant’ev, 2013, published in Zhurnal Obshchei Khimii, 2013, Vol. 83, No. 2, pp. 299–304.

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Kurochkina, G.I., Edunov, A.V., Astakhova, A.G. et al. The features of the synthesis and chemical behavior of some β-cyclodextrin silyl derivatives. Russ J Gen Chem 83, 353–359 (2013). https://doi.org/10.1134/S1070363213020199

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  • DOI: https://doi.org/10.1134/S1070363213020199

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