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A feature of reaction of 1,1′-diacetylferrocene with dimethylformamide dimethyl acetal leading to a new strategy of the synthesis of asymmetrical 1,1′-disubstituted ferrocene

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Abstract

The reaction of 1,1′-diacetylferrocene with the dimethylformamide dimethyl acetal proceeds regioselectively to afford [1-acetyl-1′-(1-dimethylamino-3-oxoprop-1-en-3-yl)]ferrocene, based on which new approaches to the synthesis of 1,1′-disubstituted unsymmetrical ferrocene derivatives via the reaction with nucleophilic reagents hydrazine hydrate, hydroxylamine, and amidines were developed.

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Authors and Affiliations

  1. Lipetsk State Pedagogical University, ul. Lenina 42, Lipetsk, 398020, Russia

    A. I. Moskalenko, A. V. Boeva & V. I. Boev

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  1. A. I. Moskalenko
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  2. A. V. Boeva
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  3. V. I. Boev
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Correspondence to A. I. Moskalenko.

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Original Russian Text © A.I. Moskalenko, A.V. Boeva, V.I. Boev, 2011, published in Zhurnal Obshchei Khimii, 2011, Vol. 81, No. 3, pp. 433–438.

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Moskalenko, A.I., Boeva, A.V. & Boev, V.I. A feature of reaction of 1,1′-diacetylferrocene with dimethylformamide dimethyl acetal leading to a new strategy of the synthesis of asymmetrical 1,1′-disubstituted ferrocene. Russ J Gen Chem 81, 529–534 (2011). https://doi.org/10.1134/S1070363211030145

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  • DOI: https://doi.org/10.1134/S1070363211030145

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