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Synthesis and structure of some 8α-analogs of steroid estrogens

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Abstract

The distances between the protons of four 8α-analogues of steroid estrogens as determined by X-ray data are consistent with the calculated values obtained by ab initio, PM3 and MM+ methods, that can be used for docking of these stereochemical analogs onto α-estrogen receptors.

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Authors and Affiliations

  1. St. Petersburg State University, Universitetskii pr. 26, St. Petersburg, 198504, Russia

    S. N. Morozkina, Sh. N. Abusalimov, G. L. Starova, S. I. Selivanov & A. G. Shavva

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  1. S. N. Morozkina
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  2. Sh. N. Abusalimov
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  3. G. L. Starova
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  4. S. I. Selivanov
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  5. A. G. Shavva
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Correspondence to A. G. Shavva.

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Original Russian Text © S.N. Morozkina, Sh.N. Abusalimov, G.L. Starova, S.I. Selivanov, A.G. Shavva, 2010, published in Zhurnal Obshchei Khimii, 2010, vol. 80, no. 7, pp. 1158–1164.

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Morozkina, S.N., Abusalimov, S.N., Starova, G.L. et al. Synthesis and structure of some 8α-analogs of steroid estrogens. Russ J Gen Chem 80, 1324–1330 (2010). https://doi.org/10.1134/S1070363210070182

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  • DOI: https://doi.org/10.1134/S1070363210070182

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