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Russian Journal of General Chemistry

, Volume 80, Issue 4, pp 836–841 | Cite as

A Study of alkylation regioselectivity of 5-substituted tetrazoles with chloroacetamides

  • N. T. Pokhodylo
  • R. D. Savka
  • V. S. Matiichuk
  • N. D. ObushakEmail author
Article

Abstract

Alkylation of 5-aryltetrazoles with N-arylchloroacetamides commonly proceeds regioselectively at 2 position of the tetrazole ring. The ratio of 1,5- and 2,5-regioisomers depends on the nature of a substituents in the benzene ring of the N-arylchloroacetamide and position of a substituent in the aryltetrazole aryl group. Features of 1H NMR spectra of the synthesized compounds are discussed.

Keywords

Alkylation General Chemistry Tetrazole Ring Chloroacetamide Chloroacetanilide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2010

Authors and Affiliations

  • N. T. Pokhodylo
    • 1
  • R. D. Savka
    • 1
  • V. S. Matiichuk
    • 1
  • N. D. Obushak
    • 1
    Email author
  1. 1.Ivan Franko Lviv National UniversityLvivUkraine

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