Abstract
Ethyl 5-cyano-6-thioxo-1,6-dihydropyridine-2-carboxylate and 2-thioxo-6-trifluoromethyl-1,2-dihydropyridine-3-carbonitrile were obtained by the SNVin reaction. The latter compound was used in the synthesis of 2-alkylsulfanyl-6-trifluoromethylpyridin-3-carbonitriles, 3-amino-5-trifluoromethylthieno[2,3-b]pyridin-2-carboxamide, and 7-thifluoromethyl-2-spirocyclopentane-1,2,3,4-tetrahydropyrido[2′,3′:2,3]thieno[4,5-d]pyrim-idin-4-one.
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Original Russian Text © V.D. Dyachenko, R.P. Tkachev, A.D. Dyachenko, 2009, published in Zhurnal Obshchei Khimii, 2009, Vol. 79, No. 1, pp. 124–127.
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Dyachenko, V.D., Tkachev, R.P. & Dyachenko, A.D. Synthesis of 2-thioxo-6-trifluoromethyl-1,2-dihydropyridine-3-carbonitrile and ethyl 5-cyano-6-thioxo-1,6-dihydropyridine-2-carboxylate by the SNVin reaction. Russ J Gen Chem 79, 121–124 (2009). https://doi.org/10.1134/S1070363209010186
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DOI: https://doi.org/10.1134/S1070363209010186