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Synthesis and spectroscopic investigation of the new polyfluoroalkyl-containing indazolones

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Abstract

Reaction of 2-perfluoroacylcycloalkane-1,3-diones and their enol methyl esters with N,N-dinucleophiles such as 4-fluorophenylhydrazine hydrochloride and pentafluorophenylhydrazine results in formation of polyfluoroalkyl-containing 1-aryl-3-polyfluoroalkyl-6,7-dihydro-1H-indazol-4(5)H-ones and 2-aryl-3-polyfluoroalkyl-6,7-dihydro-2H-indazol-4(5)H-ones respectively. Structure of compounds obtained was proved with IR, 1H, 13C, 19F, 15N NMR, and mass-spectrometric methods.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, ul. Acad. Kuprevicha 5/2, Minsk, 220141, Belarus

    T. S. Khlebnikova, V. G. Isakova, A. V. Baranovskii & F. A. Lakhvich

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  1. T. S. Khlebnikova
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  2. V. G. Isakova
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  3. A. V. Baranovskii
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  4. F. A. Lakhvich
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Correspondence to T. S. Khlebnikova.

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Original Russian Text © T.S. Khlebnikova, V.G. Isakova, A.V. Baranovskii, F.A. Lakhvich, 2008, published in Zhurnal Obshchei Khimii, 2008, vol. 78, No. 10, pp. 1718–1727.

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Khlebnikova, T.S., Isakova, V.G., Baranovskii, A.V. et al. Synthesis and spectroscopic investigation of the new polyfluoroalkyl-containing indazolones. Russ J Gen Chem 78, 1954–1963 (2008). https://doi.org/10.1134/S1070363208100241

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  • DOI: https://doi.org/10.1134/S1070363208100241

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