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Synthesis and antimicobacterial activity of 2-substituted 4-arylamino-6-methylpyrimidines

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Abstract

2-Substituted 4-arylamino-6-methylpyrimidines were synthesized by stepwise modification of the structure of 6-methyl-2-thiouracyl through the intermediate 2-(ar)alkylthio-6-methyl-4-chloropyrimidines. Some of the compounds synthesized exhibit expressed antimycobacterial activity.

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Correspondence to A. V. Erkin.

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Original Russian Text © A.V. Erkin, V.I. Krutikov, E.B. Smirnova, 2008, published in Zhurnal Obshchei Khimii, 2008, vol. 78, No. 10, pp. 1708–1712.

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Erkin, A.V., Krutikov, V.I. & Smirnova, E.B. Synthesis and antimicobacterial activity of 2-substituted 4-arylamino-6-methylpyrimidines. Russ J Gen Chem 78, 1944–1948 (2008). https://doi.org/10.1134/S1070363208100216

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  • DOI: https://doi.org/10.1134/S1070363208100216

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