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Successive reaction of 2-aryl-4-dichloromethylideneoxazol-54H-ones with 2-amino-1,3-thiazoles and strongly basic nitrogen-containing reagents

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Abstract

Treatment of 2-aryl-4-dichloromethylideneoxazole-5(4H)-ones first with 2-aminothiazoles and then with benzylamine, piperidine, or morpholine gave the corresponding 5-amino-4-(1,3-thiazol-2-ylcarbamoyl)-1,3-oxazole derivatives whose structure was confirmed by a combination of spectral data and X-ray analysis.

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Authors and Affiliations

  1. Institute of Bioorganic and Petroleum Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 1, Kiev, 02660, Ukraine

    V. M. Prokopenko, V. N. Sviripa, V. S. Brovarets & B. S. Drach

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 5, Kiev, 02660, Ukraine

    E. B. Rusanov

Authors
  1. V. M. Prokopenko
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  2. V. N. Sviripa
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  3. V. S. Brovarets
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  4. E. B. Rusanov
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  5. B. S. Drach
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Corresponding author

Correspondence to B. S. Drach.

Additional information

Original Russian Text © V.M. Prokopenko, V.N. Sviripa, V.S. Brovarets, E.B. Rusanov, B.S. Drach, 2008, published in Zhurnal Obshchei Khimii, 2008, Vol. 78, No. 4, pp. 668–673.

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Prokopenko, V.M., Sviripa, V.N., Brovarets, V.S. et al. Successive reaction of 2-aryl-4-dichloromethylideneoxazol-54H-ones with 2-amino-1,3-thiazoles and strongly basic nitrogen-containing reagents. Russ J Gen Chem 78, 649–654 (2008). https://doi.org/10.1134/S1070363208040221

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  • DOI: https://doi.org/10.1134/S1070363208040221

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