Abstract
Reformatsky reagent generated from methyl 1-bromocyclohexane-1-carboxylate reacted with N-aryl-2-oxochromene-3-carboxamides and N-aryl-6-bromo-2-oxochromene-3-carboxamides to give, depending on the conditions, the corresponding N-aryl-(6-bromo)-4-(1-methoxycarbonylcyclohexyl)-2-oxochroman-3-carboxamides or 3-aryl-(9-bromo)-1,1-pentamethylene-2,3,4,4a,5,10b-hexahydro-1H-chromeno[3,4-c]pyridine-2,4,5-triones. The products were isolated as a single diastereoisomer.
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Shchepin, V.V., Fotin, D.V., Vakhrin, M.I., and Shurov, S.N., Russ. J. Gen. Chem., 2004, vol. 74, no. 9, p. 1406.
Stewart, J.J.P., J. Comput. Chem., 1989, vol. 10, no. 2, p. 209.
Karplus, M., J. Chem. Phys., 1959, vol. 30, no. 1, p. 11.
Bothner-By, A.A., Adv. Magn. Reson., 1965, vol. 1, no. 2, p. 195.
Stewart, J.J.P., Mopac 7.0, Frank J. Seiler Res. Lab. US Air Force Academy, QCPM 175.
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Original Russian Text © V.V. Shchepin, N.F. Kirillov, M.I. Vakhrin, O.B. Bayanova, S.N. Shurov, P.S. Silaichev, 2006, published in Zhurnal Obshchei Khimii, 2006, Vol. 76, No. 7, pp. 1194–1197.
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Shchepin, V.V., Kirillov, N.F., Vakhrin, M.I. et al. Reformatsky reaction of methyl 1-bromocyclohexane-1-carboxylate with N-aryl-2-oxochromene-3-carboxamides. Russ J Gen Chem 76, 1146–1149 (2006). https://doi.org/10.1134/S1070363206070255
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DOI: https://doi.org/10.1134/S1070363206070255