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Complexation in the heparin-metal ion system

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Abstract

The reaction of high-molecular weight heparin with Mn2+, Ni2+, Fe3+, and Co2+ in aqueous solution at 37°C with 0.154 M NaCl as the supporting electrolyte was studied by pH-metry and mathematical modeling. The formation of complex species of different compositions and stabilities was detected. The stability constants of the complexes were determined.

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Authors and Affiliations

  1. Tver State University, Sadovyi per. 35, Tver, Russia

    M. A. Feofanova, Yu. V. Frantseva & S. V. Lapshin

Authors
  1. M. A. Feofanova
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  2. Yu. V. Frantseva
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  3. S. V. Lapshin
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Correspondence to M. A. Feofanova.

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Original Russian Text © M.A. Feofanova, Yu.V. Frantseva, S.V. Lapshin, 2012, published in Koordinatsionnaya Khimiya, 2012, Vol. 38, No. 5, pp. 387–392.

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Feofanova, M.A., Frantseva, Y.V. & Lapshin, S.V. Complexation in the heparin-metal ion system. Russ J Coord Chem 38, 373–378 (2012). https://doi.org/10.1134/S1070328412040033

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  • DOI: https://doi.org/10.1134/S1070328412040033

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