Abstract
Complex formation in solutions containing Ni2+ cations, glycine anions (Gly−), and β-lactam antibiotics, namely, ampicillin (Amp), amoxicillin (Axn), and cephalexin (Cpx), is studied by pH-metric titration at 20°C and an ionic strength of 0.1 (KNO3). Mixed-ligand complexes [NiGlyAmp], [NiGlyAxn], and [NiGlyCpx], which are in equilibrium with the [NiGly]+ complexes, are formed in the systems studied in a weakly alkaline medium. The formation constants of the complexes are determined. The distribution diagrams of the complex Ni(II) forms at different pH values of the solutions are constructed.
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Original Russian Text © V.G. Alekseev, I.S. Samuilova, 2007, published in Koordinatsionnaya Khimiya, 2007, Vol. 33, No. 12, pp. 930–933.
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Alekseev, V.G., Samuilova, I.S. Complex formation in nickel(II)-glycine-β-lactam antibiotic systems. Russ J Coord Chem 33, 914–917 (2007). https://doi.org/10.1134/S107032840712007X
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DOI: https://doi.org/10.1134/S107032840712007X