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Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeutical and Agrochemical Activities

Russian Journal of Bioorganic Chemistry volume 46, pages 745–767 (2020)Cite this article

Abstract

Pyridazines hold considerable interest relative to pharmacologically active molecules. The pyridazine compounds are exhibited different types of pharmacological activities. The various pyridazine drugs are shown phosphodiestrase (PDE) inhibitor, positive inotropic, vasodilation, analgesic, antiiflamatory, antimicrobial, antidepressant, antipsychotic, antianxiety, antifeeedant, herbicidal, insecticidal, plant growth regulatory, molluscicidal and other biological and agrochemical activities. Pyridazine derivatives focused consideration because of their effortless fuctionalization at various ring positions, which creates them striking compounds for designing and progress of the new pyridazine drugs in future.

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Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, 91911, PO Box 840, Rafha, Saudi Arabia

    Mohd Imran

  2. Department of Pharmacy, Himalayan Institute of Pharmacy and Research, 248007, Dehradun, (Uttarakhand), India

    Mohammad Asif

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Mohd Imran, Mohammad Asif Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeutical and Agrochemical Activities. Russ J Bioorg Chem 46, 745–767 (2020). https://doi.org/10.1134/S1068162020050167

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Keywords:

  • biological activities
  • drugs
  • pyridazines
  • structural feature