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Fluorescent Tags in Biology: Three-Dimensional Structure

Abstract

Fluorescent tags of various natures are widely used in cell biology for visualization and study processes in living organisms including gene expression, localization and migration of proteins and cells of interest, determination of the vital intracellular characteristics such as pH, ion concentration, temperature, etc. The review presents an overview of the three dimensional organization as well as advantages and disadvantages of the most promising fluorescent molecular instruments that have been widely used in biology.

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Funding

This work was carried out under the research program (state registration number AAAA-A19-119042590107-1).

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Correspondence to V. Z. Pletnev.

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Corresponding author: e-mail: vzpletnev@gmail.com.

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Pletneva, N.V., Goryacheva, E.A., Artemyev, I.V. et al. Fluorescent Tags in Biology: Three-Dimensional Structure. Russ J Bioorg Chem 46, 498–505 (2020). https://doi.org/10.1134/S1068162020040160

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  • DOI: https://doi.org/10.1134/S1068162020040160

Keywords:

  • 3D structure
  • fluorescent tags
  • biomarkers low-molecular-weight fluorophores
  • GFP-like proteins
  • photoreceptors
  • phytochromes
  • flavoproteins
  • lipocalins