Skip to main content
SpringerLink
Log in

Synthesis and antianemic activity of nanosized biocomposite ferroarabinogalactan

  • Plant Biopolymers
  • Published:
Russian Journal of Bioorganic Chemistry Aims and scope Submit manuscript

Abstract

An aggregation-stable highly resistant nanobiocomposite, a stimulator of hemopoiesis, has been synthesized and characterized by physicochemical methods. The biocomposite represents nanodisperse iron oxides encapsulated into a biocompatible biogenic matrix of arabinogalactan from Siberian larch (Larix sibirica). The effect of the novel iron-containing nanobiocomposite on the erythrocytic system in experimental anemia has been studied. It has been shown that ferroarabinogalactan produces an iron-stabilizing effect; its use qualitatively corrects iron deficiency and reduces manifestations of anemia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Plate, N.A. and Vasil’ev, A.E., Fiziologicheski aktivnye polimery (Physiologically Active Polymers), Moscow, 1986.

  2. Alekseev, G.A., Klin. Med., 1985, no. 7, pp. 129–135.

  3. Dvoretskii, L.I., Ross. Med. Zh., 2000, vol. 6, no. 20, pp. 1312–1315.

    Google Scholar 

  4. Pushkarev, V.P., Zakharov, Yu.M., and Rassokhin, A.G., Fiziol. Zh. SSSR im. I.M. Sechenova, 1991, vol. 77, no. 4, pp. 16–22.

    PubMed  CAS  Google Scholar 

  5. De Oliveira, J.E., Ventura, S., and Souza, A.M., Arch. Latin-Amer. Nutr., 1997, vol. 47, no. 2, pp. 41–43.

    Google Scholar 

  6. Yakimova, E.G., Pimenov, L.T., and Naumova, M.V., in Chelovek i lekarstvo (Man and Drug), Moscow, 1997, p. 185.

  7. Khairov, Kh.S., Vopr. Pitan., 1998, no. 3, pp. 22–25.

  8. Castro Pazos, M., Juncal Fondevila, A.R., Lopez García, B., and Oujo Pujales, J., Attention Primaria, 1996, vol. 17, no. 7, pp. 480–482.

    CAS  Google Scholar 

  9. Korolenko, T.A., Biokhimicheskie aspekty lizosomotropizma (Biochemical Aspects of Lysosomal Tropism), Novosibirsk, 1983.

  10. Pospelova, T.I., Ageeva, T.A., and Loseva, M.I., Gematol. Transfuziol., 1992, no. 9–10, pp. 194–185.

  11. Medvedeva, S.A. and Aleksandrova, G.P., in Panorama sovremennoi khimii Rossii. Sintez i modifikatsiya polimerov: sb. obzornykh statei (Panorama of Modern Chemistry in Russia. Synthesis and Modification of Polymers: Collected Review Articles), Moscow, 2003, pp. 328–352.

  12. Medvedeva, S.A., Aleksandrova, G.P., Grishchenko, L.A., and Tyukavkina, N.A., Zh. Obshch. Khim., 2002, no. 9, pp. 1569–1573.

  13. Feoktistova, L.P., Sapozhnikov, A.N., Aleksandrova, G.P., Medvedeva, S.A., and Grishchenko, L.A., Zh. Prikl. Khim., 2002, vol. 75, no. 12, pp. 1945–1954.

    Google Scholar 

  14. Aleksandrova, G.P., Grishchenko, L.A., and Medvedeva, S.A., in Sb. Nauchnykh Trudov 13 Mezhdunarodnoi Plesskoi konferentsii po nanodispersnym magnitnym zhidkostyam (Proc. 13th Int. Ples Conf. “Nanodispersed Magnetic Fluids”), Ples, 2008, pp. 280–285.

  15. Menz, E.T. and Josephson, L., US Patent No. 5679323, 1997.

Download references

Author information

Authors and Affiliations

  1. Favorskii Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, ul. Favorskogo 1, Irkutsk, 664033, Russia

    G. P. Aleksandrova, L. A. Grishchenko & T. D. Chetverikova

  2. Irkutsk State Medical University, ul. Krasnogo Vosstaniya 1, Irkutsk, 664003, Russia

    I. M. Krasnikova & S. A. Medvedeva

Authors
  1. G. P. Aleksandrova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. M. Krasnikova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. A. Grishchenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. A. Medvedeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. D. Chetverikova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to G. P. Aleksandrova.

Additional information

Original Russian Text © G.P. Aleksandrova, I.M. Krasnikova, L.A. Grishchenko, S.A. Medvedeva, T.D. Chetverikova, 2010, published in Khimija Rastitel’nogo Syr’ja, 2010, No. 3, pp. 37–42.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aleksandrova, G.P., Krasnikova, I.M., Grishchenko, L.A. et al. Synthesis and antianemic activity of nanosized biocomposite ferroarabinogalactan. Russ J Bioorg Chem 37, 829–833 (2011). https://doi.org/10.1134/S1068162011070028

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1068162011070028

Keywords

Search

Navigation