Furanocoumarins are well-known natural products that occur in the most evolved genera of Apiaceae family. This compounds were found to have cytotoxic, phytotoxic, photosensitizing, insecticidal, antibacterial and high antifungal effects. Aviprin is considered as a linear furanocoumarin substituted at C8 with an oxygenated prenyl residue. In this study we found that aviprin is a bioactive compound that exhibits high antibacterial, antifungal and phytotoxic activity. The compound stunted the germination of lettuce seeds with IC50 value of 0.270 mg/ml. The compound also inhibited the mycelia growth of Sclerotinia sclerotiorum. Aviprin indicated antibacterial activity against tested gram negative and positive bacteria with inhibition zone of 19–23.5 mm. Our results shown that aviprin can play an allelopatic role for plant.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Price excludes VAT (USA)
Tax calculation will be finalised during checkout.
Taiz, L. and Zeiger, E., Plant Physiology, 3rd ed., Sunderland: Sinauer Associates, 2002.
Strohl, W.R., Editorial in Drug Discovery Today, 2000, vol. 5, pp. 39–41.
Rahman, A.U., Studies in Natural Product Chemistry, 2000, vol. 24, Amsterdam: Elsevier.
Reigosa, M.J., Pedrol, N., and Gonzalez, L., Allelopathy, A Physiological Process with Ecological Implications, Dordrecht: Springer, 2006.
Buckingham, J., Dictionary of natural products on CD ROM Ver. 13.1 Bocakaton: Chapman and Hall CRC, 2005.
Kostova, I., Curr. Med. Chem., 2005, vol. 5, pp. 29–46.
Razavi, S.M., Nazemiyeh, H., Delazar, A., Hajiboland, R., Mukhlesur Rahman, M., Gibbona, S., Nahar, L., and Sarker, S. D., Phytochemistry Lett., 2008, vol. 1, pp. 159–162.
Koul, S.K., Dhar, K.L., and Thakur, R.S., Phytochemistry, 1979, vol. 18, pp. 1762–1763.
Harkar, S., Razdan, T.K., and Waight, E.S., Phytochemistry, 1984, vol. 23, pp. 419–426.
Razavi, S.M., Zahri, S., Zarrini, G., Nazemiyeh, H., and Mohammadi, S., Russ. J. Bioorgan. Chemistry, 2009, vol. 35, pp. 376–378.
Taiga, A., Suleiman, M.N., Sule, W., and Olufolaji, D.B., Afr. J. Biotechnol., 2008, vol. 7, pp. 3306–3308.
The article is published in the original.
About this article
Cite this article
Razavi, S.M., Zarrini, G. Bioactivity of aviprin and aviprin-3″-O-glucoside, two linear furanocoumarins from Apiaceae. Russ J Bioorg Chem 36, 359–362 (2010). https://doi.org/10.1134/S1068162010030118