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2-and 4-phenylethynylpyrenes, novel fluorescent labels for DNA

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Abstract

It was shown by the example of 1-, 2-, and 4-phenylethynylpyrene 2′-arabino-carbamate derivatives of uridine that the position of pyrene substitution substantially affects the spectral and photophysical properties of the fluorophore and its ability to interact with the nucleobase.

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Authors and Affiliations

  1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia

    I. V. Astakhova & V. A. Korshun

Authors
  1. I. V. Astakhova
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  2. V. A. Korshun
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Correspondence to V. A. Korshun.

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Original Russian Text © I.V. Astakhova, V.A. Korshun, 2008, published in Bioorganicheskaya Khimiya, 2008, Vol. 34, No. 4, pp. 570–572.

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Astakhova, I.V., Korshun, V.A. 2-and 4-phenylethynylpyrenes, novel fluorescent labels for DNA. Russ J Bioorg Chem 34, 510–512 (2008). https://doi.org/10.1134/S1068162008040171

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  • DOI: https://doi.org/10.1134/S1068162008040171

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