Abstract
New lupane β-enaminoketones were synthesized by interaction of methyl 2-hydroxymethylene-3-oxolup-20(29)-en-28-oate with aliphatic amines. Immunotropic activity was found for some of these compounds.
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Tolstikova, T.G., Sorokina, I.V., Tolstikov, G.A., Tolstikov, A.G., and Flekhter, O.V., Bioorg. Khim., 2006, vol. 32, pp. 42–55; Rus. J. Bioorg. Chem., 2006, vol. 32, pp. 37–49.
Tolstikova, T.G., Sorokina, I.V., Tolstikov, G.A., Tolstikov, A.G., and Flekhter, O.V., Bioorg. Khim., 2006, vol. 32, pp. 300–316; Rus. J. Bioorg. Chem., 2006, vol. 32, pp. 261–276.
Tolmacheva, I.A., Anikina, L.V., Vikharev, Yu.V., Shelepen’kina, L.N., Grishko, V.V., and Tolstikov, A.G., Bioorg. Khim., 2008, vol. 34, pp. 136–140; Rus. J. Bioorg. Chem., 2008, vol. 34, pp. 125–129.
Klinot, J., Svĕtlý, J., Kudláĕková, D., Budĕšínský, M., Vystrčil, A., Collect. Czech. Chem. Commun., 1979, vol. 44, pp. 211–225.
You, Y.-J., Kim, Y., Nam, N.-H., and Ahn, B.-Z., Bioorg. Med. Chem. Lett., 2003, vol. 13, pp. 3137–3140.
Laboratorni technika organické chemie (Laboratory Technique in Organic Chemistry), Keil, B., Praha: Nakladatelstvi Československé Akademie Véd, 1963; Translated under the Title Laboratornaya tekhnika organicheskoi khimii, Moscow: Mir, 1966.
Fieser, L. and Fieser, M., Reagents for Organic Synthesis, New York: Wiley and Sons, 1968.
Flekhter, O.B., Nigmatulina, L.R., Baltina, L.A., Karachurina, L.T., Galin, F.Z., Zarudii, F.S., Tolstikov, G.A., Boreko, E.I., Pavlova, N.I., Nikolaeva, S.N., and Savinova, O.V., Khim.-Farm. Zh., 2002, vol. 36, pp. 26–28.
Weygand-Hilgetag,, Organisch-Chemische Experimentierkunst. 3. Neubearbeitete Auflage, Leipzig: Johann Ambrosius Barth. Verlag, 1964.
Siegl, E., Immunologische Arbeitsmethoden, Herausgegeben von H. Friemel, Jena: Veb Gustav Fischer Verlag, 1976.
Rukovodstvo po eksperimental’nomu (doklinicheskomu) izucheniyu novykh farmakologicheskikh veshchestv, (Handbook on Experimental (Preclinical) Study of New Pharmacological Substances), Moscow: Pharmacological Committee, IZ RF, 2000.
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Original Russian Text © I.A. Tolmacheva, L.V. Anikina, Yu.B. Vikharev, E.V. Igosheva, L.N. Shelepen’kina, V.V. Grishko, A.G. Tolstikov, 2008, published in Bioorganicheskaya Khimiya, 2008, Vol. 34, No. 4, pp. 540–545.
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Tolmacheva, I.A., Anikina, L.V., Vikharev, Y.B. et al. Synthesis and immunotropic activity of methyl esters of 2-alkylaminomethylene-3-oxolup-20(29)-en-28-ic acids. Russ J Bioorg Chem 34, 483–487 (2008). https://doi.org/10.1134/S1068162008040146
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DOI: https://doi.org/10.1134/S1068162008040146