Skip to main content
SpringerLink
Log in

Variation range and “limits of the norm” of relative spleen weight in small mammals from natural populations

  • Published:
Russian Journal of Ecology Aims and scope Submit manuscript

Abstract

Variation in the relative spleen weight was studied in three small rodent species of two genera, Microtus and Myodes. Its range was found to reach 80–94/%.. Regression equations for the upper and lower limits of normal spleen weight were calculated, and its values were shown to lie between 2.0 and 2.0–5.0‰.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Alexandre-Pires, G., Pais, D., Correia, M., and Pina, J.A., Leishmaniasis: A Report about the Microvascular and Cellular Architecture of the Infected Spleen in Canis familiaris, Microsc. Res. Tech., 2006, vol. 69, no. 4, pp. 227–235.

    Article  PubMed  CAS  Google Scholar 

  • Avtandilov, G.G., Osnovy patologoanatomicheskoi praktiki (Fundamentals of Pathoanatomical Practice), Moscow: RMPAO, 1998.

    Google Scholar 

  • Barta, I., Selezenka: anatomiya, fiziologiya, patologiya i klinika (The Spleen: Anatomy, Physiology, Pathology, and Clinical; Aspects), Budapest: Akademiai Kiado, 1976, 1976.

    Google Scholar 

  • Bashenina, N.V., Evropeiskaya ryzhaya polevka (The Bank Vole), Moscow: Nauka, 1981.

    Google Scholar 

  • Dunaevskaya, O.F., Morphometric Characteristics of the Spleen in Chronically Irradiated Dogs, in Aktual’nye voprosy veterinarnoi meditsiny: Mat-ly Sibirskogo mezhdun. veter. kongr. (Current Problems in Veterinary Medicine: Proc. Siberian Int. Vet. Congr.), Novosibirsk, 2005, p. 304.

  • Elmore, S.A., Enhanced Histopathology of the Spleen, Toxicol. Pathol., 2006, vol. 34, pp. 648–655.

    Article  PubMed  Google Scholar 

  • Eremeeva, M.E., Gerns, H.L., Lydy, S.L., et al., Bacteremia, Fever, and Splenomegaly Caused by a Newly Recognized Bartonella Species, N. Engl. J. Med., 2007, vol. 356, no. 23, pp. 2381–2387.

    Article  PubMed  CAS  Google Scholar 

  • Gashev, S.N., Mlekopitayushchie v sisteme ekologicheskogo monitoringa (na primere Tyumenskoi oblasti) (Mammals in the System of Ecological Monitoring: The Example of Tyumen Oblast). Tyumen: Tyumen. Gos. Univ., 2000.

    Google Scholar 

  • Grigorkina, E.B. and Pashnina, I.A., On the Problem of Radioadaptation in Small Mammals (ecological specialization of species, radioresistance, hematopoiesis, and immunity), Radiats. Biol. Radioekol., 2007, vol. 47, no. 3, pp. 371–378.

    CAS  Google Scholar 

  • Ivanter, E.V., Ivanter, T.V., and Tumanov, I.L., Adaptivnye osobennosti melkikh mlekopitayushchikh (Specific Adaptive Features of Small Mammals), Leningrad: Nauka, 1985.

    Google Scholar 

  • Kaliteevskii, P.F., Makroskopicheskaya differentsial’naya diagnostika patologicheskikh protsessov (Microscopic Differential Diagnosis of Pathological Processes), Moscow: Meditsina, 1987.

    Google Scholar 

  • Klimovich, M.A., Smotryaeva, M.A, Gaintseva, V.D., and Shishkina, L.N., Evaluations of Tests for Assessing Biological Consequences of Variable Low-Dose-Rate X-Ray Irradiation in Animals, Radiats. Biol. Radioekol., 2009, vol. 49, no. 4, pp. 473–477.

    CAS  Google Scholar 

  • Materii, L.D. and Taskaev, A.I., Morphological Changes in the Hematopoietic System and Their Probable Remote Consequences in Murine Rodents from the Chernobyl Zone, in Bioindikatsiya radioaktivnykh zagryaznenii (Bioindication of Radioactive Contamination), Moscow, 1999, pp. 260–273.

  • Michael, B., Yano, B., Sellers, R.S., et al., Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practices, Toxicol. Pathol., 2007, vol. 35, pp. 742–750.

    Article  PubMed  Google Scholar 

  • Nishikawa, S., Okada, M., Sakairi, T., et al., Lymphoid Hyperplasia of the Spleen of an 8-Week-Old Rat, J. Toxicol. Pathol., 2008, vol. 21, pp. 243–247.

    Article  Google Scholar 

  • Olenev, G.V. and Pasichnik, N.M., Ecological Analysis of Spleen Hypertrophy in Cyclomorphic Rodents Taking into Account the Type of Ontogeny, Russ. J. Ecol., 2003, vol. 34, no. 3, pp. 188–197.

    Article  Google Scholar 

  • Orekhova, N.A., Analysis of Metabolic Homeostasis in Rodents with Different Ecological Specializations Living in a Radioactive Environment, Extended Abstract of Cand. Sci. (Biol.) Dissertation, Yekaterinburg, 2010.

  • Pashnina, I.A. and Sineva, N.V., Specific Physiological Features of the Northern Mole Vole (Ellobius talpinus Pall.) from a Radioactive Environment, in Biota gornykh territorii: istoriya i sovremennoe sostoyanie: Sb. tr. konf. mol. uch. (The Biota of Mountain Areas: History and Current State, Proc. Young Sci. Conf.), Yekaterinburg, 2002, pp. 137–140.

  • Porfirio, Z., Ribeiro, M.P., Estevam, C.S., et al., Hepatosplenomegaly Caused by an Extract of Cyanobacterium microcystis aeruginosa Bloom Collected in the Manguaba Lagoon, Alagoas, Brazil, Rev. Microbiol., 1999, vol. 30, no. 3, pp. 278–285.

    Article  Google Scholar 

  • Pyastolova, O.A., Vershinin, V.L., Trubetskaya, E.A., and Gatiyatullina, E.Z., Utilization of Amphibians in Bioindication Research on Territories of the Eastern Urals Radioactive Trace, Russ. J. Ecol., 1996, vol. 27, no. 5, pp. 361–365.

    Google Scholar 

  • Schmidt-Nielsen, K., Scaling: Why Is Animal Size So Important?, Cambridge: Cambridge Univ. Press, 1984. Translated under the title Razmery zhivotnykh: pochemu oni tak vazhny?, Moscow: Mir, 1987.

    Google Scholar 

  • Shvarts, S.S., Smirnov, V.S., and Dobrinskii, L.N., Metod morfofiziologicheskikh indikatorov v ekologii nazemnykh pozvonochnykh (The Method of Morphophysiological Indicators in the Ecology of Terrestrial Vertebrates), Sverdlovsk: Ural. Fil. Akad. Nauk SSSR, 1968.

    Google Scholar 

  • Suttie, A.W., Histopathology of the Spleen, Toxicol. Pathol., 2006, vol. 34, no. 5, pp. 466–503.

    Article  PubMed  Google Scholar 

  • Ward, J., Reznik, G., and Garner, F.M., Proliferative Lesions of the Spleen in Male F344 Rats Fed Diets Containing P-Chloroaniline, Vet. Pathol., 1980, vol. 17, no. 2, pp. 200–205.

    PubMed  CAS  Google Scholar 

  • Yablokov, A.V., Izmenchivost’ mlekopitayushchikh (Variation in Mammals), Moscow: Akad. Nauk SSSR, 1966.

    Google Scholar 

  • Yarmonenko, S.P. and Vainson, A.A., Radiobiologiya cheloveka i zhivotnykh (Human and Animal Radiobiology), Moscow: Vysshaya Shkola, 2004.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sukachev Institute of Forest, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/28, Krasnoyarsk, 663036, Russia

    E. V. Ekimov, A. N. Borisov & A. S. Shishikin

Authors
  1. E. V. Ekimov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. N. Borisov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. S. Shishikin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. V. Ekimov.

Additional information

Original Russian Text © E.V. Ekimov, A.N. Borisov, A.S. Shishikin, 2012, published in Ekologiya, 2012, No. 3, pp. 229–235.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ekimov, E.V., Borisov, A.N. & Shishikin, A.S. Variation range and “limits of the norm” of relative spleen weight in small mammals from natural populations. Russ J Ecol 43, 250–255 (2012). https://doi.org/10.1134/S1067413612030071

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1067413612030071

Keywords

Search

Navigation