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High-Resolution Raman Spectra of Metformin

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Abstract

High-resolution spectra of molecular vibrations in metformin, one of the most widely used antidiabetic drugs, which also possesses antiaging and antitumor properties, have been obtained by a high-sensitivity Raman-scattering technique. It is established that rather narrow (4–10 cm–1) spectral lines observed in a 300–1200 cm–1 range can be used for separating spectral components corresponding to the vibrations of particular functional groups. This circumstance makes metformin an interesting model for studying molecular biosensors.

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Correspondence to B. Kh. Bairamov.

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Original Russian Text © F.B. Bayramov, V.V. Toporov, O.B. Chakchir, V.N. Anisimov, B.Kh. Bairamov, 2018, published in Pis’ma v Zhurnal Tekhnicheskoi Fiziki, 2018, Vol. 44, No. 12, pp. 3–8.

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Bayramov, F.B., Toporov, V.V., Chakchir, O.B. et al. High-Resolution Raman Spectra of Metformin. Tech. Phys. Lett. 44, 505–507 (2018). https://doi.org/10.1134/S1063785018060160

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  • DOI: https://doi.org/10.1134/S1063785018060160

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