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A mass spectrometer for pain-response monitoring in rats

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Abstract

A mass spectrometer with a membrane interface has been used for measuring the relative concentration of carbon dioxide (CO2) released from rat skin in response to thermal irritation and pain stimulus during intraperitoneal propofol–lidocaine anesthesia. It is established that the local anesthetic lidocaine directly influences the central nervous system and induces antinociceptive reaction to thermal irritation.

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Authors and Affiliations

  1. Ioffe Physical Technical Institute, Russian Academy of Sciences, St. Petersburg, 194021, Russia

    A. Yu. Elizarov

Authors
  1. A. Yu. Elizarov
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Correspondence to A. Yu. Elizarov.

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Original Russian Text © A.Yu. Elizarov, 2017, published in Pis’ma v Zhurnal Tekhnicheskoi Fiziki, 2017, Vol. 43, No. 12, pp. 3–8.

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Elizarov, A.Y. A mass spectrometer for pain-response monitoring in rats. Tech. Phys. Lett. 43, 545–546 (2017). https://doi.org/10.1134/S1063785017060190

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  • DOI: https://doi.org/10.1134/S1063785017060190

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