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Activation of Animal Brain Neuromediators by Interferential Transcranial Currents

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Abstract

A method of transcranial electromagnetic stimulation of the mammalian brain is proposed. The method is based on the interference of currents caused by high-frequency orthogonal oscillations of electric fields, which are modulated by low-frequency meander pulses. The effectiveness of the method was confirmed by the results of experiments on stimulating the brain of rats and rabbits.

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REFERENCES

  1. A. Wood, R. Mate, K. Karipidis. J. Exposure Sci. Environmental Epidemiolology, 16, 1 (2021). https://doi.org/10.1038/s41370-021-00307-7

    Article  CAS  Google Scholar 

  2. V. N. Bingi, A. V. Savin. UFN, 173 (3), 265 (2003).

    Article  Google Scholar 

  3. V. N. Bingi. Principles of electromagnetic biophysics (Fizmatlit, M., 2011).

  4. V. P. Lebedev, Y. S. Katsnelson. Transcranial Electric Simulation: Analgesia and Allied Effects. In: Automatization in Physiological Investigations (Leningrad, Nauka, 1988), p. 198.

    Google Scholar 

  5. A. O. Vonti, A. V. Ilinsky, J. S. Katznelson, E. B. Shadrin. Tech. Phys. Lett., 44 (17), 27 (2018).

    Article  Google Scholar 

  6. T. Brinker, E. Stopa, J. Morrison, P. Klinge. CNS, 11, 10 (2014). https://doi.org/10.1186/2045-8118-11-10

    Article  CAS  Google Scholar 

  7. L. N. Airapetov, A. M. Zaitchik, M. S. Trukhmanov, V. P. Lebedev, V. A. Sorokoumov, Y. S. Katsnelson, V. G. Abisogomian, Y. K. Kodzayev. Fiziol. Zhurn. SSSR, 71 (1), 56 (1985).

    CAS  Google Scholar 

  8. D. A. Gruenewald, A. M. Matsumoto. Hypothalamic Changes Relevant to Reproduction in Aging Male Rodents in Functional Neurobiology of Aging., ed. by P.R. Hof and Ch. V. Mobbs (Academic Press, 2000).

  9. V. P. Lebedev, Y. S. Katsnelson, V. A. Leosko, A. L. Baranovsky, G. I. Shiemis. Fiziol. Zhurn. SSSR, 59 (8), 1120 (1983).

    Google Scholar 

  10. S. J. Van Albada, P. A. Robinson. Frontiers in Human Neuroscience, 7 (2013). https://doi.org/10.3389/fnhum.2013.00056

  11. S. A. Chkhenkeli, M. Šramka, G. S. Lortkipanidze, T. N. Rakviashvili, E. S. Bregvadze, G. E. Magalashvili, I. S. Chkhenkeli. Clinical Neurology and Neurosurgery, 106 (4), 318 (2004). https://doi.org/10.1016/j.clineuro.2004.01.009

    Article  PubMed  Google Scholar 

  12. V. P. Lebedev, A. B. Savchenko, A. B. Fan, S. Yu. Zhilyaev. Physiol. Journal USSR, 74 (8), 1094 (1988).

    CAS  Google Scholar 

  13. A. S. Sprouse-Blum, G. Smith, D. Sugai, F. Don Parsa. Hawaii Med. J., 69 (3), 70 (2010).

    PubMed  PubMed Central  Google Scholar 

  14. S. Maxwell, D. Bigg, K. Stanczykiewicz, S. Carlberg-Racich. S.J. Addict Dis. J., 25 (3), 89 (2006). https://doi.org/10.1300/J069v25n03_l1

    Article  Google Scholar 

  15. A. S. Vladyka, A. A. Shandra, R. E. Khoma, V. M. Vorontsov. Nociception and antinociception: theory and practice (FOP “Kashtelyanov A.I.”, Vinnitsa, 2012).

  16. D. L. Nelson. CNS and Neurological Disorders, 3 (1), 53 (2004).

    CAS  PubMed  Google Scholar 

  17. Y. Katsnelson, H. Beckhoff, E. Berk, Y. Palkin, N. Lisyanskaya, A. Tereo, N. Baranova. Proceedins of VIth International Regional (Asia) ISBS Neuroscience Conference “Stress and Behavior”, p. 26.

  18. N. N. Danilova. Physiology of Higher Nervous Activity (Phoenix, Rostov-on-Don, 2005).

    Google Scholar 

  19. V. P. Dudiev. Psychomotor: dictionary reference (National Psychological Encyclopedia, 2008).

    Google Scholar 

  20. A. V. Semyanov, V. B. Kazantsev. Neuron-glial interaction in the brain. Educational and methodological material for the advanced training program “Storage and processing of information in biological systems” (NNSU, Nizhny Novgorod, 2007).

    Google Scholar 

  21. Inhibitors. Concise Chemical Encyclopedia, I. L. Knunyants (chief editor) (Sov. Encyclopedia, Moscow, 1961–1967), vol. 2, p. 228–229.

  22. M. Lavzin, S. Rapoport, A. Polsky, L. Garion, J. Schiller. Nature, 490 (7420), 397 (2012).https://doi.org/10.1038/nature11451

    Article  ADS  CAS  PubMed  Google Scholar 

  23. J. Malmivuo, R. Plonsey. Bioelectromagnetism (Oxford University Press, NY., Oxford, 1995).

  24. A. V. Saveliev. Journal of Open Systems Evolution, 8 (2), 96 (2006).

    Google Scholar 

  25. B. N. Levy, B. M. Koeppen, B. A. Stanton. Principles of Physiology (Elsevier, 2005), p. 836.

    Google Scholar 

  26. V. S. Sohal, F. Zhang, O. Yizhar, K. Deisseroth. Nature, 459 (7247), 698 (2009). https://doi.org/10.1038/nature07991

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  27. A. O. Vonti, A. V. Ilinsky, V. M. Kapralova, E. B. Shadrin. Tech. Phys., 88 (6), 934 (2018).

    Google Scholar 

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ACKNOWLEDGMENTS

The authors thank H. Beckhoff and V. Chuev (Brain Advance Wellness Technologies, 3801 Stump Rd, Doylestown, PA 18902, USA) for their assistance and advice.

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Correspondence to E. B. Shadrin.

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All applicable international, national, and/or institutional guidelines for animal care and management were observed.

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Katsnelson, Y., Ilinskiy, A.V. & Shadrin, E.B. Activation of Animal Brain Neuromediators by Interferential Transcranial Currents. Tech. Phys. 68 (Suppl 1), S76–S87 (2023). https://doi.org/10.1134/S1063784223090098

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