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Effect of Shock Waves Generated by Pulsed Electric Discharges in Water on Yeast Cells and Virus Particles

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Abstract

The aim of this study is to determine the optimal parameters of the electric pulses and shock waves generated by them for the soft destruction of the virus and yeast envelopes with no changes in the structure of antigenic surface albumin and in the cell morphology in order to use them to produce antivirus vaccines and in biotechnology. The pulse electric discharges in water have been studied for different values of amplitude, pulse duration and the rate of the rise in the current. A mathematical model has been developed to estimate the optimal parameters of pulsed electric charges and shock waves for the complete destruction of the yeast cell envelopes and virus particles at a minimum of pulses.

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Authors and Affiliations

  1. Institute of Electrophysics and Electric Power, Russian Academy of Sciences, St. Petersburg, 191186, Russia

    A. E. Girdyuk, V. A. Kolikov & V. N. Snetov

  2. Research Institute of Influenza, Ministry of Healthcare of the Russian Federation, St. Petersburg, 197376, Russia

    A. N. Gorshkov & V. V. Egorov

  3. St. Petersburg Technical University, St. Petersburg, 195251, Russia

    G. A. Shneerson

  4. St. Petersburg Nuclear Physics Institute, National Research Center Kurchatov Institute, Gatchina, 188300, Russia

    V. V. Egorov

Authors
  1. A. E. Girdyuk
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  2. A. N. Gorshkov
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  3. V. V. Egorov
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  4. V. A. Kolikov
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  5. V. N. Snetov
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  6. G. A. Shneerson
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Corresponding author

Correspondence to V. A. Kolikov.

Additional information

Original Russian Text © A.E. Girdyuk, A.N. Gorshkov, V.V. Egorov, V.A. Kolikov, V.N. Snetov, G.A. Shneerson, 2018, published in Zhurnal Tekhnicheskoi Fiziki, 2018, Vol. 63, No. 2, pp. 291–299.

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Girdyuk, A.E., Gorshkov, A.N., Egorov, V.V. et al. Effect of Shock Waves Generated by Pulsed Electric Discharges in Water on Yeast Cells and Virus Particles. Tech. Phys. 63, 285–290 (2018). https://doi.org/10.1134/S1063784218020159

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  • DOI: https://doi.org/10.1134/S1063784218020159

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