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Dip-Pen Nanolithography Method for Fabrication of Biofunctionalized Magnetic Nanodiscs Applied in Medicine

  • XXV International Symposium “Nanostructures: Physics and Technology”, Saint Petersburg, Russia, June 26–30, 2017. Nanostructure Technology
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Abstract

The magnetic properties of ferromagnetic nanodiscs coated with gold, manufactured using the Dip-Pen Nanolithography method, and were studied by atomic-force and magnetic force microscopy methods. The magnetic discs (dots) are represented as nanoagents (nanorobots) applied in medicine for the cancer cell destruction. The motivation of this work stem from the necessity of the understanding of the magnetization distribution in ferromagnetic discs that is crucial for their application in biomedicine. We have performed the theoretical calculations in order to compare the theoretical image contrast to experimental results. Herein, we report about the fabrication and analysis of biocompatible ferromagnetic nanodiscs with the homogenous magnetized state.

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References

  1. F. Q. Hu, L. Wei, Z. Zhou, Y. L. Ran, Z. Li, and M. Y. Gao, Adv. Mater. 18, 2553 (2006).

    Article  Google Scholar 

  2. J. Yu, C. Yang, J. Li, Y. Ding, L. Zhang, M. Z. Yousaf, J. Lin, R. Pang, L. Wei, L. Xu, F. Sheng, C. Li, G. Li, L. Zhao, and Y. Hou, Adv. Mater. 26, 4114 (2014).

    Article  Google Scholar 

  3. D. Liu, W. Wu, J. Ling, S. Wen, N. Gu, and X. Zhang, Adv. Funct. Mater. 21, 1498 (2011).

    Article  Google Scholar 

  4. S. Carinelli, M. Martı, S. Alegret, and M. I. Pividori, New Biotechnol. 32, 521 (2015).

    Article  Google Scholar 

  5. J. B. Haun, C. M. Castro, R. Wang, V. M. Peterson, B. S. Marinelli, H. Lee, and R. Weissleder, Sci. Transl. Med. 3 (71), ra16 (2011).

    Article  Google Scholar 

  6. C. T. Yavuz, J. T. Mayo, W. Y. William, A. Prakash, J. C. Falkner, S. Yean, L. Cong, H. J. Shipley, A. Kan, M. Tomson, D. Natelson, and V. L. Colvin, Science 314, 964 (2006).

    Article  Google Scholar 

  7. R. Hergt, S. Dutz, R. Muller, and M. Zeisberger, J. Phys.: Condens. Matter 18, 2919 (2006).

    ADS  Google Scholar 

  8. C. S. Kumar and F. Mohammad, Adv. Drug. Deliver. Rev. 63, 789 (2011).

    Article  Google Scholar 

  9. M. Arruebo, R. Fernandez-Pacheco, M. R. Ibarra, and J. Santamaria, Nano Today 2, 22 (2007).

    Article  Google Scholar 

  10. J. Dobson, Drug. Dev. Res. 67, 55 (2006).

    Article  Google Scholar 

  11. M. J. Li, A. Nath, and W. M. Atkins, Biochemistry 56, 2506 (2017).

    Article  Google Scholar 

  12. R. BrittoHurtado, M. Cortez-Valadez, and H. Arizpe-Chavez, Gold Bull. 50, 85 (2017).

    Article  Google Scholar 

  13. X. L. Liu and H. M. Fan, Curr. Opin. Chem. Eng. 4, 38 (2014).

    Article  Google Scholar 

  14. E. A. Rozhkova, I. V. Ulasov, S. D. Baderl, M. S. Lesniak, and D. H. Kim, Nat. Mater. 10, 165 (1964).

    Google Scholar 

  15. V. Suresh, M. S. Huang, and M. P. Srinivasan, J. Mater. Chem. 22, 21871 (2012).

    Article  Google Scholar 

  16. M. Buerger, M. Ruth, S. Declair, J. Forstner, C. Meier, and D. J. As, Appl. Phys. Lett. 102, 081105 (2013).

    Article  ADS  Google Scholar 

  17. L. X. Zou, X. M. Lv, and Y. Z. Huang, Opt. Lett. 38, 3807 (2013).

    Article  ADS  Google Scholar 

  18. S. W. Chung, A. Mirkin, and H. Zhang, Nano Lett. 3, 43 (2010).

    Google Scholar 

  19. J. J. Saenz, N. Garcia, P. Grutter, E. Meyer, H. Heinzelmann, R. Weisendanger, L Rosenthaler, H. R. Hidber, and H.-J. Guntherodt, J. Appl. Phys. 62, 4293 (1987).

    Article  ADS  Google Scholar 

  20. A. Wadas, J. Magn. Magn. Mater. 71, 147 (1988).

    Article  ADS  Google Scholar 

  21. I. I. Saenz, N. Garcia, and J. C. Slonczewski, Appl. Phys. Lett. 53, 1449 (1988).

    Article  ADS  Google Scholar 

  22. D. Rugar, H. J. Mamin, P. Guethner, S. E. Lambert, and J. E. Stern, J. Appl. Phys. 68, 1169 (1990).

    Article  ADS  Google Scholar 

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Authors and Affiliations

  1. Siberian Federal University, Krasnoyarsk, 660041, Russia

    T. E. Smolyarova, A. V. Lukyanenko, A. S. Tarasov & A. E. Sokolov

  2. Kirensky Institute of Physics, Russian Academy of Science, Krasnoyarsk, 660036, Russia

    T. E. Smolyarova, A. V. Lukyanenko, A. S. Tarasov & A. E. Sokolov

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  1. T. E. Smolyarova
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  2. A. V. Lukyanenko
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  3. A. S. Tarasov
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  4. A. E. Sokolov
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Correspondence to T. E. Smolyarova.

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Smolyarova, T.E., Lukyanenko, A.V., Tarasov, A.S. et al. Dip-Pen Nanolithography Method for Fabrication of Biofunctionalized Magnetic Nanodiscs Applied in Medicine. Semiconductors 52, 675–677 (2018). https://doi.org/10.1134/S1063782618050305

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  • DOI: https://doi.org/10.1134/S1063782618050305

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