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Nuclear-physical analysis methods in medical geology: Assessment of the impact of environmental factors on human health

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Abstract

The procedure for geomedical studies is outlined, and the niche occupied by the nuclear-physical analysis methods in these studies is pointed out. The necessity of construction of an efficient complex of the most modern analytical methods is demonstrated. The metrological parameters of methods applied in the analysis of natural environments and biological materials are evaluated. The current state of pollution of natural environments with heavy and toxic metals is characterized in two specific industrial hubs: the towns of Gus-Khrustalny and Podolsk. The levels of pollution of diagnostic biological materials (hair and blood) from children living in various urban districts are studied in the light of specific features of the manufacturing industry in these towns and the life environment of child population. The results of studies focused on evaluating the effect of environment on the health of child population are detailed. The actual damage to child health, their neuropsychic development and behavior, and the effect of socioeconomic factors are determined. Preventive problems among the child population exposed to lead and other toxic metals are evaluated, and ways to solve them are proposed. A system of early diagnosis and preventive measures for the mitigation of adverse effect of toxic metals (Pb, Cu, Mn, Zn, Cr, Ni, As, etc.) on the neuropsychic development of children is developed based on an actual ecogeochemical estimation of the state of the region under study.

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References

  1. A. P. Avtsin, A. A. Zhavoronkov, M. A. Rish, and L. S. Strochkova, Human Microelementoses (Meditsina, Moscow, 1991) [in Russian].

    Google Scholar 

  2. B. A. Revich, S. L. Avaliani, and G. I. Tikhonova, The Basics of Evaluation of the Effect of Polluted Environment on Human Health (Tsentr Ekol. Politiki Rossii, Moscow, 2004) [in Russian].

    Google Scholar 

  3. J. Emsley, The Elements (Clarendon Press, Oxford, 1991).

    Google Scholar 

  4. Yu. A. Ershov and T. N. Pletneva, Mechanisms of Toxic Action of Inorganic Compounds (Meditsina, Moscow, 1989) [in Russian].

    Google Scholar 

  5. T. V. Guseva, A. V. Pechnikov, and V. N. Tsevelev, “Evaluating the effect of crystal production on the distribution of lead at adjacent territories,” Khim. Prom-st., No. 6, 382–388 (1994).

    Google Scholar 

  6. Evaluating the Effect of Environmental Pollution in the Podolsk Industrial Hub on the State of Public Health, Ed. by B.A. Revich and Yu.L. Mizernitskii (Inst. Ekol. Chel., Moscow, 1992) [in Russian].

    Google Scholar 

  7. GOST 17.4.1.02-83. Nature Protection. Soils. Classification of Chemicals for Pollution Control (Izd. Standartov, Moscow, 1984) [in Russian].

  8. GN 2.1.5.1315-03. Maximum Permissible Concentrations (MPCs) of Chemical Compounds in Water of Water Bodies for Drinking, Household, Cultural, and General Use (Minzdrav Rossii, Moscow, 2003) [in Russian].

  9. GOST 17.1.5.05-85. Nature Protection. Hydrosphere. General Requirements for Surface and Sea Waters, Ice and Atmospheric Precipitation Sampling (Izd. Standartov, Moscow, 1985) [in Russian].

  10. GOST 17.1.5.01-80. Nature Protection. Hydrosphere. General Requirements for Sampling of Bottom Sediments of Water Objects for Their Pollution Analysis (Izd. Standartov, Moscow, 1980) [in Russian].

  11. GN 2.1.6.1338-03. Maximum Permissible Concentrations (MPCs) of Pollutants in the Atmospheric Air in Populated Areas (Minzdrav Rossii, Moscow, 2003) [in Russian].

  12. R. Cornelis, B. Heinzow, R. F. M. Herber, J. M. Christensen, O. M. Poulsen, E. Sabbioni, D. M. Templeton, Y. Thomassen, M. Vahter, and O. Vesterberg, “Sample collection guidelines for trace elements in blood and urine (technical report),” Pure Appl. Chem. 67, 1575–1608 (1995).

    Article  Google Scholar 

  13. Y. S. Ryabukhin, “International coordinated program on activation analysis of trace element pollutants in human hair,” in Hair, Trace Elements, and Human Illness, Ed. by A.C. Brown and R.G. Grounse (Praeger, New York, 1980), pp. 3–34.

    Google Scholar 

  14. M. K. Beklemishev, V. M. Ivanov, S. V. Muginova, E. A. Osipova, M. A. Proskurnin, and E. N. Shapovalova, Natural Environments and Their Analytical Monitoring, Vol. 2: Methods of Analysis of Natural Environments. Textbook (Art-Ofis, Krasnodar, 2007) [in Russian].

    Google Scholar 

  15. L. A. Shirkin, X-Ray Fluorescence Analysis of Natural Environments. Textbook (Vladimirskii Gos. Univ., Vladimir, 2009) [in Russian].

    Google Scholar 

  16. Activation Analysis. Methodology and Application (FAN, Tashkent, 1990) [in Russian].

  17. E. V. Chuparina and A. M. Martynov, “Application of nondestructive X-ray fluorescence analysis for determining the element composition of medicinal plants,” J. Anal. Chem. 66, 389–395 (2011).

    Article  Google Scholar 

  18. MUK 4.1.763-4.1.779-99. Determination of Chemical Compounds in Biological Media (Minzdrav Rossii, Moscow, 2000) [in Russian].

  19. NSAM 155-KhS. Determination of Copper, Zinc, Cadmium, Bismuth, Antimony, Lead, Cobalt, Nickel, Iron, and Manganese via Atomic Absorption in Solid Granular Materials (Vseross. Nauchno-Issled. Inst. Miner. Syr’ya, Moscow, 1988) [in Russian].

  20. RD 52.18.289-90. Procedure of Measurement of the Mass Fraction of Mobile Forms of Metals (Copper, Lead, Zinc, Nickel, Cadmium, Cobalt, Chromium, and Manganese) in Soil Samples via Atomic Absorption (Gos. Komitet SSSR Gidrometeorol., Moscow, 1990) [in Russian].

  21. NSAM 510-YaF. Determination of Microelements in Rocks, Ores, Soils, Bottom Sediments, Plant Ash, and Solid Biological Materials of Vegetable and Animal Origin via Neutron Activation (Moscow, 2011) [in Russian].

  22. A. V. Gorbunov, S. M. Lyapunov, O. I. Okina, M. V. Frontasyeva, and S. S. Pavlov, “Nuclear and related analytical techniques in ecology: impact of geoecological factors on the balance of trace elements in the human organism,” Phys. Part. Nucl. 43, 783–824 (2012).

    Article  Google Scholar 

  23. I. F. Seregina, S. Yu. Lanskaya, O. I. Okina, M. A. Bol’shov, S. M. Lyapunov, V. L. Chugunova, and A. S. Foktova, “Determination of chemical elements in biological fluids and diagnostic substrates from children by inductively coupled plasma mass spectrometry,” J. Anal. Chem. 65, 964–972 (2010).

    Article  Google Scholar 

  24. Handbook on Metals in Clinical and Analytical Chemistry, Ed. by H. Seiler, A. Sigel, and H. Sigel (CRC Press, New York, 1994).

    Google Scholar 

  25. E. Cortes Toro, J. J. M. De Goeij, J. Bacso, Yuan-Di Cheng, L. Kinova, J. Matsubara, S. Niese, T. Sato, G. R. Wesenberg, Y. Muramatsu, and R. M. Parr, “The significance of hair mineral analysis as a mean for assessing internal body burdens of environmental pollutants: results from an IAEA Coordinated Research Programme,” J. Radioanal. Nucl. Chem. 167, 413–421 (1993).

    Article  Google Scholar 

  26. I. Rodushkin and M. D. Axelsson, “Application of double focusing sector field ICP-MS for multielemental characterization of human hair and nails. Part I. Analytical methodology,” Sci. Total Environ. 250, 83–100 (2000).

    Article  Google Scholar 

  27. GOST R ISO/IEC 17025. General Requirements for the Competence of Testing and Calibration Laboratories (Standartinform, Moscow, 2012) [in Russian].

  28. GN 2.1.7.2511-09. Approximate Permissible Concentrations (APCs) of Chemical Compounds in Soil (Moscow, 2009) [in Russian].

  29. SanPiN 2.1.7.1287-03. Sanitary and Epidemiological Requirements for Soil Quality (Moscow, 2004) [in Russian].

  30. SP 11-102-97. Engineering and Environmental Survey for Constructions (PNIIIS Gosstroya Rossii, Moscow, 1997) [in Russian].

  31. Review of the Background State of Natural Environment in CIS Countries in 2003, Ed. by Yu. A. Izrael’ (Gidrometeoizdat, St. Petersburg, 2005) [in Russian].

    Google Scholar 

  32. Review of the Background State of Natural Environment in CIS Countries in 2007, Ed. by Yu. A. Izrael’ (Rosgidromet, Moscow, 2009) [in Russian].

    Google Scholar 

  33. Review of the Background State of Natural Environment in CIS Countries in 2008, Ed. by Yu. A. Izrael’ (Rosgidromet, Moscow, 2010) [in Russian].

    Google Scholar 

  34. N. A. Taranenko, N. V. Efimova, and O. A. Rychagova, “On the study of the chemical pollution of air medium in indoor areas of child facilities in the cities of Irkutsk oblast,” Ekol. Chel., No. 4, 3–7 (2009).

    Google Scholar 

  35. V. A. Fedorova, “The use of rare and rare-earth elements in glass industry,” Steklyannaya Tara, No. 5, 14–16 (2010).

    Google Scholar 

  36. V. S. Gamayurova, Arsenic in Ecology and Biology (Nauka, Moscow, 1993) [in Russian].

    Google Scholar 

  37. F. Ya. Rovinskii, L. V. Burtseva, V. A. Petrukhin, Yu. P. Cherkhanov, and T. B. Chicheva, “Background concentration of lead, mercury, arsenic, and cadmium in natural environments (according to world data),” in Monitoring of the Background Pollution of Natural Environments. Vol. 1 (Gidrometeoizdat, Leningrad, 1982), pp. 14–35 [in Russian].

    Google Scholar 

  38. V. S. Savenko, “On the background concentration of rare-earth elements in the atmosphere,” in Monitoring of the Background Pollution of Natural Environments. Vol. 6 (Gidrometeoizdat, Leningrad, 1990), pp. 50–59 [in Russian].

    Google Scholar 

  39. GOST 202-84. Zink White. Specifications (Izd. Standartov, Moscow, 1984) [in Russian].

  40. Guidelines for the Evaluation and Control of Lead-Based Paint Hazards in Housing (U.S. Department of Housing and Urban Development, Washington, 1995).

  41. I. N. Il’chenko, S. M. Lyapunov, S. V. Matveeva, A. D. Deev, O. I. Okina, and P. Yu. Gorobets, Methods for the Detection of Ecology-Dependent Abnormalities in the Neuropsychic Development of Children. A Guidebook for Physicians (Terra, Moscow, 2004) [in Russian].

    Google Scholar 

  42. Preventing Lead Poisoning in Young Children. A Statement by the Centers for Disease Control and Prevention (CDC, Atlanta, 1991).

  43. Medical Management Guidelines for Lead-Exposed Adults (Association of Occupational and Environmental Clinics, Washington, 2007).

  44. B. A. Revich, “Chemical elements in human hair as an indicator of the effect of pollution of working and ambient environments,” Gig. Sanit., No. 3, 55–59 (1990).

    Google Scholar 

  45. Clinical Guide to Laboratory Tests, Ed. by N. W. Tietz (Saunders, Philadelphia, 1983; Unimed-Press, Moscow, 2003).

    Google Scholar 

  46. T. K. Chernyaeva, N. A. Matveeva, Yu. G. Kuzmichev, and M. P. Gracheva, “Concentration of heavy metals in child hair in an industrial city,” Gig. Sanit., No. 3, 26–28 (1997).

    Google Scholar 

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Authors and Affiliations

  1. Geological Institute, Russian Academy of Sciences, Moscow, 119017, Russia

    A. V. Gorbunov, S. M. Lyapunov & O. I. Okina

  2. Joint Institute for Nuclear Research, Dubna, 141980, Russia

    M. V. Frontas’eva & S. S. Pavlov

  3. First Medical Institute, Russian Academy of Medical Sciences, Moscow, 119991, Russia

    I. N. Il’chenko

Authors
  1. A. V. Gorbunov
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  2. S. M. Lyapunov
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  3. O. I. Okina
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  4. M. V. Frontas’eva
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  5. S. S. Pavlov
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  6. I. N. Il’chenko
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Correspondence to A. V. Gorbunov.

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Original Russian Text © A.V. Gorbunov, S.M. Lyapunov, O.I. Okina, M.V. Frontas’eva, S.S. Pavlov, I.N. Il’chenko, 2015, published in Fizika Elementarnykh Chastits i Atomnogo Yadra, 2015, Vol. 46, No. 3.

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Gorbunov, A.V., Lyapunov, S.M., Okina, O.I. et al. Nuclear-physical analysis methods in medical geology: Assessment of the impact of environmental factors on human health. Phys. Part. Nuclei 46, 424–451 (2015). https://doi.org/10.1134/S1063779615030065

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