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X-Ray Study of 7a-(2-Chlorophenyl)-7a,8a,9,10,11,12ahexadronaptho[ 1',2':4,5]furo[3,2-d]pyrrolo[2,1-b]oxazole and 2-(4-fluorophenyl)-2-hydroxynaptho[2,1-b]furan-1(2H)-one

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Abstract

Two organic compounds, namely, 7a-(2-chlorophenyl)-7a,8a,9,10,11,12a-hexadronaptho-[1',2':4,5]furo[3,2-d]pyrrolo[2,1-b]oxazole (I) and 2-(4-fluorophenyl)-2-hydroxynaptho[2,1-b]furan- 1(2H)-one (II), were synthesised via microwave reaction using commercially available glyoxal monohydrate, β-Naphthol, pyrrolidine, and Cu(OAc)2 · H2O, and their crystal structures were determined by X-ray diffraction technique. The crystals of compound I are orthorhombic, sp. gr. P212121, a = 6.8750(5) Å, b = 8.2248(9) Å, c = 31.720(3) Å, and Z = 4, while the crystals of compound II are monoclinic, sp. gr. P21/c, a = 7.4038(9) Å, b = 18.592(2) Å, c = 10.4589(12) Å, β = 107.492(13)°, and Z = 4. The inter molecular O–H···O, C–H···O, and C–H···F hydrogen interactions play significant role in stabilizing the crystal structure in the compound II. In addition, aromatic π–π interactions are also observed in the structure of the compound II.

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Authors and Affiliations

  1. X-ray Crystallography Laboratory, Post-Graduate Department of Physics and Electronics, University of Jammu, Jammu Tawi, 180006, India

    Balbir Kumar & Vivek K. Gupta

  2. Medicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM), Jammu, 180001, India

    Narsaiah Battini, Qazi Naveed Ahmed & Asif Ali

  3. Academy of Scientific and Innovative Research (AcSIR), 2-Rafi Marg, New Delhi, India

    Narsaiah Battini & Qazi Naveed Ahmed

  4. Natural Product Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India

    Asif Ali

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  1. Balbir Kumar
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  2. Narsaiah Battini
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  3. Qazi Naveed Ahmed
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  4. Asif Ali
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  5. Vivek K. Gupta
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Correspondence to Vivek K. Gupta.

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Kumar, B., Battini, N., Ahmed, Q.N. et al. X-Ray Study of 7a-(2-Chlorophenyl)-7a,8a,9,10,11,12ahexadronaptho[ 1',2':4,5]furo[3,2-d]pyrrolo[2,1-b]oxazole and 2-(4-fluorophenyl)-2-hydroxynaptho[2,1-b]furan-1(2H)-one. Crystallogr. Rep. 63, 382–387 (2018). https://doi.org/10.1134/S1063774518030045

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  • DOI: https://doi.org/10.1134/S1063774518030045

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