Abstract
The title compound 6-phenyl-4-(p-tolyl)pyridin-2(1H)-one was synthesized via one-pot, three component reaction of (E)-1-phenyl-3-(p-tolyl)-2-propen-1-one, ethyl 2-nitroacetate and ammonium acetate in refluxing ethanol, as a shiny green crystalline solid in 83% yield. Its structure was characterized by spectral studies and unambiguously corroborated by X-ray diffraction crystallography. The crystals of title compound are monoclinic, sp. gr. P21/n, a = 11.8346(7) Å, b = 13.4413(9) Å, c = 17.7626(10) Å, β = 99.479(5)°, and Z = 8. All the rings in molecule of the title compound are planar. Hydrogen interactions play significant role in stabilizing the crystal structure and the supramolecular aggregate of molecules is facilitated by strong N–H···O and C–H···O type of hydrogen interactions.
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Khajuria, R., Sharma, S., Kapoor, K.K. et al. Single Crystal X-ray Study of 6-Phenyl-4-(p-tolyl)pyridin-2(1H)-one. Crystallogr. Rep. 62, 1144–1147 (2017). https://doi.org/10.1134/S1063774517070227
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DOI: https://doi.org/10.1134/S1063774517070227