Skip to main content
SpringerLink
Log in

Synthesis, characterization, and crystal structure of 2-amino-7-methyl-5-oxo-4-phenyl-4,5-dihydropyrano[3,2-c]pyran-3-carbonitrile

  • Structure of Organic Compounds
  • Published:
Crystallography Reports Aims and scope Submit manuscript

Abstract

2-Amino-7-methyl-5-oxo-4-phenyl-4,5-dihydropyrano[3,2-c]pyran-3-carbonitrile, C16H12N2O3 is synthesized via one-pot multi-component reaction at room temperature using commercially available urea as inexpensive and environmentally benign organo-catalyst. Its structure is determined by single-crystal X-ray diffraction technique The crystals are monoclinic, a = 10.7357(12), b = 8.7774(8), c = 15.0759(16) Å, β = 103.575(11)°, Z = 4, sp. gr. P21/n, R = 0.0551 for 1696 observed reflections. The crystal structure is stabilized by N–H···N, C–H···O, and C–H···π interactions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. G. Brahmachari, Handbook of Pharmaceutical Natural Products (Wiley-VCH Verlag GmbH, Weinheim, 2010).

    Google Scholar 

  2. T. Raj, R. K. Bhatia, A. Kapur, et al., Eur. J. Med. Chem. 45, 790 (2010).

    Article  Google Scholar 

  3. W. Kemnitzer, J. Drewe, S. Jiang, et al., J. Med. Chem. 50, 2858 (2007).

    Article  Google Scholar 

  4. D. Kumar, V. B. Reddy, S. Sharad, et al., Eur. J. Med. Chem. 44, 3805 (2009).

    Article  Google Scholar 

  5. G. Brahmachari and B. Banerjee, ACS Sustainable Chem. Eng. 2, 411 (2014).

    Article  Google Scholar 

  6. G. M. Sheldrick, Acta Crystallogr. A 64, 112 (2008).

    Article  ADS  Google Scholar 

  7. L. J. Farrugia, J. Appl. Crystallogr. 30, 565 (1997).

    Article  Google Scholar 

  8. L. J. Farrugia, J. Appl. Crystallogr. 32, 837 (1999).

    Article  Google Scholar 

  9. M. Nardelli, J. Appl. Crystallogr. 28, 659 (1995).

    Article  Google Scholar 

  10. A. L. Spek, Acta Crystallogr. D 65, 148 (2009).

    Article  Google Scholar 

  11. S. K. Mohamed, M. Akkurt, M. N. Tahir, et al., Acta Crystallogr. E 68, o1965 (2012).

    Article  Google Scholar 

  12. J. N. Low, J. Cobo, M. Nogueras, et al., Acta Crystallogr. C 59, o38 (2003).

    Article  Google Scholar 

  13. F. H. Allen, O. Kennard, D. G. Watson, et al., J. Chem. Soc. Perkin Trans., 2, S1–19 (1987).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. X-ray Crystallography Laboratory, Post-Graduate Department of Physics and Electronics, University of Jammu, Jammu Tawi, 180 006, India

    S. Sharma, Rajni Kant & V. K. Gupta

  2. Laboratory of Natural Products & Organic Synthesis, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan West Bengal, 731 235, India

    B. Banerjee & G. Brahmachari

Authors
  1. S. Sharma
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Banerjee
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. Brahmachari
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Rajni Kant
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. K. Gupta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. K. Gupta.

Additional information

The article is published in the original.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sharma, S., Banerjee, B., Brahmachari, G. et al. Synthesis, characterization, and crystal structure of 2-amino-7-methyl-5-oxo-4-phenyl-4,5-dihydropyrano[3,2-c]pyran-3-carbonitrile. Crystallogr. Rep. 60, 1126–1130 (2015). https://doi.org/10.1134/S1063774515070238

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1063774515070238

Keywords

Search

Navigation