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Crystallography Reports

, Volume 59, Issue 1, pp 117–124 | Cite as

Synchrotron X-ray diffraction study of the structure of oral stratum corneum model lipid membranes

  • N. Yu. RyabovaEmail author
  • A. Yu. Gruzinov
  • A. V. Zabelin
Liquid Crystals
  • 68 Downloads

Abstract

Membranes modeling the lipid fraction of the mucous membrane of the human oral cavity have been studied by X-ray synchrotron diffraction. Ternary systems, composed of a mixture of sphingomyelin, dipalmitoylphosphatidylcholine, and dipalmitoylphosphatidylethanolamine with component weight ratios of 1: 2: 2 and 1: 2: 1, have lamellar structures in the gel phase at the physiological temperature (37°C). An inverted hexagonal phase is formed in the system with 40% dipalmitoylphosphatidylethanolamine in the temperature range of 60–70°C. This phase coexists with the liquid-crystalline lamellar phase in a narrow temperature range and completely surpresses the lamellar phase with an increase in temperature to 80°C. Multi-component oral stratum corneum membranes are characterized by several lamellar phases at 20–37°C and the coexistence of one or several lamellar phases with inverted hexagonal phase at 80–90°C.

Keywords

Stratum Corneum Crystallography Report Lamellar Structure Hexagonal Phase DPPE 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Inc. 2014

Authors and Affiliations

  • N. Yu. Ryabova
    • 1
    • 2
    Email author
  • A. Yu. Gruzinov
    • 3
  • A. V. Zabelin
    • 3
  1. 1.Joint Institute for Nuclear ResearchDubna, Moscow oblastRussia
  2. 2.Skobeltsyn Institute of Nuclear PhysicsMoscow State UniversityMoscowRussia
  3. 3.National Research Centre “Kurchatov Institute”MoscowRussia

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