Skip to main content
SpringerLink
Log in

Evolution of high-intensity focusing systems for different applications in medicine (Review)

  • Acoustics of Animate Systems. Bioacoustics
  • Published:
Acoustical Physics Aims and scope Submit manuscript

Abstract

The evolution of high-intensity focusing systems for application in medicine has been outlined from their introduction (in the 1950s) to date. This work is in fact a review with two sections. The focusing systems for medical application discussed under the first section are based on using single focusing transducers with a radiating element shaped as a section of a spherical shell. Attention is mainly given to the devices developed at the Andreev Acoustics Institute in the 1970s–1980s; focusing systems developed abroad in the past few decades and most widely clinically used are also briefly discussed there. The second section of the review is devoted to focusing systems based on phased arrays which allow users not only to electronically steer the focus within a selected range, but also, especially importantly for various medical applications, to simultaneously create several foci. The main attention under the second section is given to the two-dimensional phased arrays with randomized location of elements on the surface, which the Acoustics Institute developed in active collaboration with others. It has been shown that irregularity in the location of elements either substantially improves the quality of spatial intensity distributions by reducing the level of secondary maxima of intensity in the array-induced fields or allows to considerably reduce the number of elements in the array with the same quality of distributions. The paper discusses principles of designing such arrays, methods of their calculations and possible applications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. W. J. Fry, J. Am. Phys. Med. 37(3), 143 (1958).

    MathSciNet  Google Scholar 

  2. W. J. Fry and F. J. Fry, in Ultrasound in Biology and Medicine (Washington, 1957), pp. 99–103.

  3. W. J. Fry and F. Dunn, in Physical Techniques in Biological Research (Academic, New York, 1962), Vol. 4, Ch. 6, pp. 261–394.

    Google Scholar 

  4. R. Warwick and J. Pond, J. Anat. 102, 387 (1968).

    Google Scholar 

  5. L. D. Rozenberg, Sound Focusing Systems (Akad. Nauk SSSR, Moscow, 1949) [in Russian].

    Google Scholar 

  6. L. D. Rozenberg, in Physics and Techniques of Powerful Ultrasound, Ed. by L. D. Rozenberg, vol. 1: Sources of Powerful Ultrasound (Nauka, Moscow, 1967), pp. 149–206 [in Russian].

    Google Scholar 

  7. L. D. Rozenberg and M. G. Sirotyuk, Akust. Zh. 5, 206 (1959) [Sov. Phys. Acoust. 5, 206 (1959)].

    Google Scholar 

  8. L. R. Gavrilov and E. M. Tsirul’nikov, Focused Ultrasound in Physiology and Medicine (Nauka, Leningrad, 1980) [in Russian].

    Google Scholar 

  9. I. A. Vartanyan, L. R. Gavrilov, G. V. Gershuni, A. S. Rosenblum, and E. M. Tsirulnikov, Sensor Reception. An Experience of Investigations with the Help of Focused Ultrasound (Nauka, Leningrad, 1985) [in Russian].

    Google Scholar 

  10. V. M. Avirom, O. S. Adrianov, N. I. Vykhodtseva, L. R. Gavrilov, T. A. Mering, and M. G. Sirotyuk, Zh. Vyssh. Nervn. Deyat. 21, 1110 (1971).

    Google Scholar 

  11. L. R. Gavrilov, Akust. Zh. 20, 27 (1974) [Sov. Phys. Acoust. 20, 16 (1974)].

    Google Scholar 

  12. N. I. Vykhodtseva, L. R. Gavrilov, T. A. Mering, and N. G. Yamshchikova, Zh. Nevropatol. Psikhiatr. 76, 1810 (1976).

    Google Scholar 

  13. Yu. S. Inin, M. G. Sirotyuk, and S. I. Tyurina, Byull. Éksp. Biol. Med. 38(4), 120 (1971).

    Google Scholar 

  14. S. I. Tyurina, F. A. Brazovskaya, Yu. S. Inin, D. I. Paikin, M. G. Sirotyuk, and L. R. Gavrilov, Byull. Éksp. Biol. Med. 75(5), 120 (1973).

    Google Scholar 

  15. Yu. S. Inin, S. I. Tyurina, M. G. Sirotyuk, and L. R. Gavrilov, USSR Inventor’s Certificate No. 412891 from 06.05.1970, Byull. Izobret. No. 4 (1974).

  16. L. R. Gavrilov, N. P. Narbut, and F. E. Fridman, Akust. Zh. 20, 374 (1974) [Sov. Phys. Acoust. 20, 229 (1974)].

    Google Scholar 

  17. L. R. Gavrilov, G. S. Kalendo, V. V. Ryabukhin, K. A. Shaginyan, and S. P. Yarmonenko, Akust. Zh. 21, 187 (1975) [Sov. Phys. Acoust. 21, 119 (1975)].

    Google Scholar 

  18. L. R. Gavrilov, N. I. Vykhodtseva, I. I. Konopatskaya, V. N. Dmitriev, V. A. Elagin, L. V. Solontsova, and V. P. Yushin, Med. Radiolog., No. 6, 49 (1987).

  19. A. N. Gerchikov, L. V. Solontsova, S. V. Kozin, V. A. Zolotov, and L. R. Gavrilov, Med. Radiolog. 35(8), 13 (1990).

    Google Scholar 

  20. L. R. Gavrilov, G. V. Gershuni, O. B. Il’inskiĭ, L. A. Popova, M. G. Sirotyuk, and E. M. Tsirul’nikov, Akust. Zh. 19, 519 (1973) [Sov. Phys. Acoust. 19, 332 (1973)].

    Google Scholar 

  21. L. R. Gavrilov, E. M. Tsirul’nikov, and E. E. Shchekanov, Akust. Zh. 21, 706 (1975) [Sov. Phys. Acoust. 21,437 (1975)].

    Google Scholar 

  22. L. R. Gavrilov, G. V. Gersuni, O. B. Ilyinskiĭ, M. G. Sirotyuk, E. M. Tsirulnikov, and E. E. Shchekanov, in Progress in Brain Research (Elsevier, Amsterdam, Oxford, New York, 1976), Vol. 43, pp. 272–292.

    Google Scholar 

  23. L. R. Gavrilov, G. V. Gersuni, O. B. Ilyinskiĭ, and E. M. Tsirulnikov, Brain Res. 135, 265 (1977).

    Article  Google Scholar 

  24. L. R. Gavrilov, G. V. Gersuni, O. B. Ilyinski, E. M. Tsirulnikov, and E. E. Shchekanov, Brain Res. 135, 279 (1977).

    Article  Google Scholar 

  25. L. R. Gavrilov, Ultrasonics 22(3), 132 (1984).

    Article  Google Scholar 

  26. I. Davies, L. R. Gavrilov, and E. M. Tsirulnikov, Pain 67, 17 (1996).

    Article  Google Scholar 

  27. L. R. Gavrilov, E. M. Tsirulnikov, and I. Davies, Ultrasound Med. Biol. 22, 179 (1996).

    Article  Google Scholar 

  28. L. R. Gavrilov, G. V. Gershuni, V. I. Pudov, A. S. Rosenblyum, and E. M. Tsirulnikov, Vestn. Otorinolar., No. 2, 3 (1983).

  29. E. M. Tsirulnikov, I. A. Vartanyan, G. V. Gersuni, A. S. Rosenblyum, V. I. Pudov, and L. R. Gavrilov, Ultrasound Med. Biol. 14(4), 277 (1988).

    Article  Google Scholar 

  30. V. A. Galkin, V. I. Petrov, G. A. Nikolaev, V. I. Losh- chilov, S. I. Tyurina, and L. R. Gavrilov, USSR Inventor’s Certificate No. 602180 from 04.06.1976, Byull. Izobret. No. 14 (1978).

  31. S. I. Zakharov, K. Yu. Bogdanov, L. V. Rosenshtraukh, L. R. Gavrilov, and V. P. Yushin, Ultrasound Med. Biol. 15, 561 (1989).

    Article  Google Scholar 

  32. L. R. Gavrilov, L. A. Bokeriya, A. A. Dogadov, F. V. Beskrovnov, and I. I. Konopatskaya, in Proc. of the 3rd Session of Russ. Acoust. Soc. (Moscow, 1994), pp. 56–58.

  33. L. R. Gavrilov, V. N. Dmitriev, and L. V. Solontsova, J. Acoust. Soc. Am. 83, 1167 (1988).

    Article  ADS  Google Scholar 

  34. W. L. Nyborg, Ultrasound Med. Biol. 26, 927 (2000).

    Article  Google Scholar 

  35. K. Hynynen, Ultrasound Med. Biol. 17, 157 (1991).

    Article  Google Scholar 

  36. F. J. Fry, Ultrasound Med. Biol. 3, 179 (1977).

    Article  Google Scholar 

  37. F. J. Fry and S. A. Goss, Ultrasound Med. Biol. 6, 33 (1980).

    Article  Google Scholar 

  38. L. R. Gavrilov, G. V. Gershuni, O. B. Il’inskiĭ, E. M. Tsirulnikov, and E. E. Shchekanov, Reception and Focused Ultrasound (Nauka, Leningrad, 1976) [in Russian].

    Google Scholar 

  39. M. R. Bailey, V. A. Khokhlova, O. A. Sapozhnikov, S. G. Kargl, and L. A. Crum, Akust. Zh. 49, 437 (2003) [Acoust. Phys. 49, 369 (2003)].

    Google Scholar 

  40. Physical Principles of Medical Ultrasonics, Ed. by C. R. Hill, J. C. Bamber, and G. R. ter Haar (Wiley, New York, 2004).

    Google Scholar 

  41. R. Bihrle, R. S. Foster, N. T. Sanghvi, F. J. Fry, and J. P. Donohue, Urology 43, 21 (1994).

    Article  Google Scholar 

  42. N. T. Sanghvi, R. S. Foster, R. Bihrle, R. Casey, T. Uchida, M. H. Phillips, J. Syrus, A. V. Zaitsev, K. W. Marich, and F. J. Fry, J. Eur. Ultrasound, No. 9, 19 (1999).

  43. A. Gelet, J. Y. Chapelon, J. Margomari, Y. Theillere, F. Gorry, R. Souchon, and R. Bouvier, Eur. Urol. 23(Suppl. 1), 44 (1993).

    Google Scholar 

  44. A. Gelet, J. Y. Chapelon, R. Bouvier, C. Pangaud, and Y. Lasne, J. Urol. 161, 156 (1999).

    Article  Google Scholar 

  45. F. Wu, Z. B. Wang, W. Z. Chen, J. Z. Zou, J. Bai, H. Zhu, K. Q. Li, F. L. Xie, C. B. Jin, and H. B. Su, Ultrasound Med. Biol. 30, 245 (2004).

    Article  Google Scholar 

  46. F. Wu, W. Z. Chen, J. Bai, J. Z. Zou, Z. L. Wang, H. Zhu, and Z. B. Wang, Ultrasound Med. Biol. 27, 1099 (2001).

    Article  Google Scholar 

  47. L. R. Gavrilov, J. W. Hand, P. Abel, and C. A. Cain, IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 44, 1010 (1997).

    Article  Google Scholar 

  48. L. R. Gavrilov and J. Hand, Akust. Zh. 46, 182 (2000) [Acoust. Phys. 46, 144 (2000)].

    Google Scholar 

  49. E. B. Hutchinson, M. T. Buchanan, and K. Hynynen, Med. Phys. 23, 767 (1996).

    Article  Google Scholar 

  50. E. B. Hutchinson and K. Hynynen, IEEE Trans. Ultras. Ferroelec. Freq. Contr. 43, 1032 (1996).

    Article  Google Scholar 

  51. M. I. Skolnik, Introduction to Radar Systems, 2nd ed. (McGraw-Hill, New York, 1980).

    Google Scholar 

  52. F. Dupenloup, J. Y. Chapelon, D. Cathignol, and O. Sapoznikov, IEEE Trans Ultras. Ferroelec. Freq. Contr. 43, 991 (1996).

    Article  Google Scholar 

  53. S. A. Goss, L. A. Frizell, J. T. Kouzmanoff, J. M. Barich, and J. M. Yang, IEEE Trans. Ultras. Ferroelec. Freq. Contr. 43, 1111 (1996).

    Article  Google Scholar 

  54. L. R. Gavrilov and J. W. Hand, IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 47, 125 (2000).

    Article  Google Scholar 

  55. L. R. Gavrilov and J. Hand, Akust. Zh. 46, 456 (2000) [Acoust. Phys. 46, 390 (2000)].

    Google Scholar 

  56. L. R. Gavrilov, J. Hand, and I. G. Yushina, Akust. Zh. 46, 632 (2000) [Acoust. Phys. 46, 551 (2000)].

    Google Scholar 

  57. J. W. Hand and L. R. Gavrilov, Great Britain Patent No. GB2347043 (23 Aug. 2000); US Patent No. 6488630 (3 Dec. 2002).

  58. L. R. Gavrilov, Akust. Zh. 49, 604 (2003) [Acoust. Phys. 49, 508 (2003)].

    Google Scholar 

  59. E. A. Filonenko, L. R. Gavrilov, V. A. Khokhlova, and J. Hand, Akust. Zh. 50, 272 (2004) [Acoust. Phys. 50,222 (2004)].

    Google Scholar 

  60. E. S. Ebbini and C. A. Cain, IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 36, 540 (1989).

    Article  Google Scholar 

  61. E. S. Ebbini and C. A. Cain, IEEE Trans. Biomed. Eng. 38, 634 (1991).

    Article  Google Scholar 

  62. D. R. Daum and K. Hynynen, IEEE Trans. Ultras. Ferroelec. Freq. Contr. 45, 208 (1998).

    Article  Google Scholar 

  63. D. R. Daum and K. Hynynen, IEEE Trans. Ultras. Ferroelec. Freq. Contr. 46, 1254 (1999).

    Article  Google Scholar 

  64. R. J. McGough, M. L. Kessler, E. S. Ebbini, and C. A. Cain, IEEE Trans. Ultras. Ferroelec. Freq. Contr. 43, 1074 (1996).

    Article  Google Scholar 

  65. M. Pernot, J.-F. Aubry, M. Tanter, J.-L. Thomas, and M. Fink, Phys. Med. Biol. 48, 2577 (2003).

    Article  Google Scholar 

  66. J. W. Hand, A. Shaw, N. Sadhoo, S. Rajagopal, R. J. Dickinson, and L. R. Gavrilov, Phys. Med. Biol. 54, 5675 (2009).

    Article  Google Scholar 

  67. H.-Li Liu, H. Chang, W.-S. Chen, T.-C. Shih, J.-K. Hsiao, and W.-L. Lin, Med. Phys. 34, 3436 (2007).

    Article  Google Scholar 

  68. J.-F. Aubry, M. Pernot, F. Marquet, M. Tanter, and M. Fink, Phys. Med. Biol. 53, 2937 (2008).

    Article  Google Scholar 

  69. S. Bobkova, L. Gavrilov, V. Khokhlova, A. Shaw, and J. Hand, Ultrasound Med. Biol. 36(6), 888 (2010).

    Article  Google Scholar 

  70. T. Iwamoto and H. Shinoda, World Haptics 2005 (Italy, March 2005), pp. 220–228.

  71. T. Iwamoto and H. Shinoda, in Proc. of the Symp. on Haptic Interfaces for Virtual Environment and Teleoperator Systems, IEEE Haptics Symp. 2006 (2006), pp. 57–61.

  72. L. R. Gavrilov and E. M. Tsirulnikov, in Nonlinear Acoustics at the Beginning of 21st Century, Ed. by O. V. Rudenko and O. A. Sapozhnikov (Mosk. State Univ., Moscow, 2002), Vol. 1, pp. 445–448.

    Google Scholar 

  73. L. R. Gavrilov, Akust. Zh. 54, 315 (2008) [Acoust. Phys. 54, 269 (2008)].

    MathSciNet  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Andreev Acoustics Institute, ul. Shvernika 4, Moscow, 117036, Russia

    L. R. Gavrilov

Authors
  1. L. R. Gavrilov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to L. R. Gavrilov.

Additional information

Original Russian Text © L.R. Gavrilov, 2010, published in AkusticheskiĭZhurnal, 2010, Vol. 56, No. 6, pp. 844–861.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gavrilov, L.R. Evolution of high-intensity focusing systems for different applications in medicine (Review). Acoust. Phys. 56, 1097–1111 (2010). https://doi.org/10.1134/S1063771010060369

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1063771010060369

Keywords

Search

Navigation