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Hypoxia during mammalian preimplantation development: Extreme circumstance vs. typical environment

  • Embryogenesis and Carcinogenesis
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Abstract

The given paper summarizes the data on the early mammalian embryo development in culture media containing low oxygen concentration. Experimental results on in vitro modeling the hypoxia for preimplantation development are reviewed. Hypoxic conditions were shown to be available in the female reproductive tract of different mammalian species. The estimation of the embryo developing in vitro exhibits that lower oxygen level in culture media improves embryonic quality.

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Correspondence to A. G. Pogorelov.

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Original Russian Text © A.G. Pogorelov, A.A. Smirnov, V.N. Pogorelova, 2016, published in Ontogenez, 2016, Vol. 47, No. 2, pp. 117–121.

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Pogorelov, A.G., Smirnov, A.A. & Pogorelova, V.N. Hypoxia during mammalian preimplantation development: Extreme circumstance vs. typical environment. Russ J Dev Biol 47, 99–102 (2016). https://doi.org/10.1134/S1062360416020077

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  • DOI: https://doi.org/10.1134/S1062360416020077

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