Interlinear differences in generative function formation in pubescence of male mice

Abstract

The formation of generative function in pubescence is studied in males of three inbred mice lines BALB/cLac, CBA/Lac, and PT. From days 35 through 60 of life every 5 days the amount of sperm cells and the quantity of abnormal heads of spermatozoa in males are calculated in both epididymises and the morphometry of the testicles, epididymises, and seminal vesicles is carried out. Interlinear deviations in the pubertal dynamics of the parameters of spermatogenesis and the morphometric indexes are determined, indicating a weak spermatogenesis process in males of CBA/Lac in comparison with males from the other lines. Males from the line CBA/Lac are characterized by a low amount of epididymal spermatozoa combined with low frequency of abnormal spermatozoon heads; these traits can be considered as a compensatory process that increases fertility. By the end of the period, i.e., on days 55–60 of life, the males of all three inbred mice lines have not reached the definitive level in the number of epididymal spermatozoa; the weight of the testicles, epididymise, and seminal vesicles; and body weight. Thus, in laboratory mice, the beginning of reproductive activity is not connected with these reproductive indexes reaching the definitive level. The results of the study show that in adult mature males of laboratory mice the interlinear deviations in generative function emerge in the pubertal period and persist thereafter.