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Phenolics Composition and Biological Activities Assessment of Leaves, Flowers and Roots Extracts from Erodium glaucophyllum, Erodium hirtum and Erodium guttatum

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Abstract

Erodium glaucophyllum, Erodium hirtum and Erodium guttatum were medicinal herbs from a southern Mediterranean known for its health benefits. There is a strong demand for the find of new anti-pathogenic bacteria metabolites. In the present study, the different ethanolic extracts of leaves, flowers, and Roots from the three plants were evaluated. The phenolics contents (total phenolic content, total flavonoids, and condensed tannins), antioxidant potentials, and in microbiological media to determine their effects on bacteria (Escherichia coli K12, pseudomonas aeruginosa DSM1128, Staphylococcus aureus 29213 ATCC, Enterococcus aerogenes 13048 ATCC, Enterococcus faecalis 40589, and Proteus mirabilis 3128) were investigated. The results showed that, the different extracts of the three species exhibited high content in polyphenols, flavonoids, and tannins. The leaves extract of Erodium glaucophyllum has the highest levels of polyphenols, flavonoids, and tannins; 154.2 ± 0.5 µg GAE/g DR, 68.2 ± 3.6 µg RE/g DR, and 36.2 ± 1.4 µg CE/g DR, respectively. In addition, the leaves extract of Erodium glaucophyllum possesses highest antioxidant activities (totals antioxidant capacity, 2,2-diphenyl-1-picrylhydrazyl (DPPH)) to compare with the other extracts. Furthermore, the three medicinal plants exhibited a high antimicrobial potential against pathogenic bacteria. The maximum inhibition showed in the Erodium glaucophyllum leaves extract against Enterococcus aerogenes 13048 ATCC, pseudomonas aeruginosa DSM1128, and Proteus mirabilis 3128. A significant positive correlation was found between the polyphenols content, antioxidant activity and antimicrobial activity of the different extracts.

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Funding

This study supported by University of Tunis EL Manar, University of Applied Sciences, Neubrandenburg, Germany, for the infrastructure and facilities, and Laboratory of Aromatic and Medicinal Plants, Center of Biotechnology (LR15CBBC06) at the Ecopark of Borj-cédria. BP-901, 2050 Hammam-Lif. Tunisia.

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Authors and Affiliations

  1. Faculté des Sciences Mathématiques Physiques et Naturelles de Tunis, University of Tunis El Manar, Tunis, Tunisia

    Hamza Gadhoumi

  2. Laboratory of Aromatic and Medicinal Plants, Center of Biotechnology at the Ecopark of Borj-cédria, BP-901, 2050, Hammam-Lif, Tunisia

    Hamza Gadhoumi, Moufida Saidani Tounsi & EL Akrem Hayouni

  3. Department of Agriculture and Food Sciences, Neubrandenburg University of Applied Sciences, Neubrandenburg, Germany

    Enriqueta Martinez-Rojas

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  1. Hamza Gadhoumi
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  2. Enriqueta Martinez-Rojas
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  3. Moufida Saidani Tounsi
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  4. EL Akrem Hayouni
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Correspondence to Hamza Gadhoumi.

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The authors declare that they have no conflict of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Hamza Gadhoumi, Martinez-Rojas, E., Tounsi, M.S. et al. Phenolics Composition and Biological Activities Assessment of Leaves, Flowers and Roots Extracts from Erodium glaucophyllum, Erodium hirtum and Erodium guttatum. Biol Bull Russ Acad Sci 48, 667–672 (2021). https://doi.org/10.1134/S1062359021060091

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