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Topology and planar polarity of the Xenopus embryonic ciliated epithelium

  • Developmental Biology
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Abstract

The effect of mechanical stress on the topology and planar polarity (PP) of the Xenopus embryonic ciliated epithelium was studied. It was found that the explantation of different sections of the blastocoel roof of the early gastrula disrupted the normal orientation of rows of ciliated cells (CCs) and led to the partition of zones with a single PP into several sections with different polarity or to the occurrence of chaotic patterns. Mechanical stretching of explants increased the order of their PP and oriented it predominantly perpendicular to the stretching axis. Changes in mechanical stress had no significant effect on the ciliated epithelium topology.

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References

  • Aigouy, B., Farhadifar, R., Staple, D.B., et al., Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila, Cell, 2010, vol. 142, no. 5, pp. 773–786.

    Article  PubMed  CAS  Google Scholar 

  • Deblandre, G.A., Wettstein, D.A., Koyano-Nakagawa, N., and Kintner, C., A two-step mechanism generates the spacing pattern of the ciliated cells in the skin of Xenopus embryos, Development, 1999, vol. 126, no. 21, pp. 4715–4728.

    PubMed  CAS  Google Scholar 

  • Eley, L., Yates, L.M., and Goodship, J.A., Cilia and disease, Current Opinion Gen. Dev., 2005, vol. 15, no. 3, pp. 308–314.

    Article  CAS  Google Scholar 

  • Engler, A.J., Sen, S., Sweeney, H.L., and Discher, D.E., Matrix elasticity directs stem cell lineage specification, Cell, 2006, vol. 126, no. 4, pp. 677–689.

    Article  PubMed  CAS  Google Scholar 

  • Farhadifar, R., Roper, J.C., Aigouy, B., et al., The influence of cell mechanics, cell-cell interactions, and proliferation on epithelial packing, Current Biol., 2007, vol. 17, no. 24, pp. 2095–2104.

    Article  CAS  Google Scholar 

  • Nieuwkoop, P.D. and Faber, J., Normal Table of Xenopus laevis (Daudin), Amsterdam: North-Holland Publ. Co., 1956.

    Google Scholar 

  • Savost’yanov, G.A., Osnovy strukturnoi gistologii. Prostranstvennaya organizatsiya epiteliev (Fundamentals of Structural Histology. The Spatial Organization of Epithelia), St. Petersburg: Nauka, 2005.

    Google Scholar 

  • Staple, D.B., Farhadifar, R., Röper, J.C., et al., Mechanics and remodelling of cell packings in epithelia, Eur. Phys. J. E, 2010, vol. 33, no. 2, pp. 117–127.

    Article  PubMed  CAS  Google Scholar 

  • Stubbs, J.L., Davidson, L., Keller, R., and Kintner, C., Radial intercalation of ciliated cells during Xenopus skin development, Development, 2006, vol. 133, no. 13, pp. 2507–2515.

    Article  PubMed  CAS  Google Scholar 

  • Wang, Y. and Nathans, J., Tissue/planar cell polarity in vertebrates: new insights and new questions, Development, 2007, vol. 134, no. 4, pp. 647–658.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Biological Faculty, Moscow State University, Moscow, 119992, Russia

    A. Yu. Evstifeeva

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  1. A. Yu. Evstifeeva
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Correspondence to A. Yu. Evstifeeva.

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Original Russian Text © A.Yu. Evstifeeva, 2013, published in Izvestiya Akademii Nauk, Seriya Biologicheskaya, 2013, No. 6, pp. 661–667.

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Evstifeeva, A.Y. Topology and planar polarity of the Xenopus embryonic ciliated epithelium. Biol Bull Russ Acad Sci 40, 508–514 (2013). https://doi.org/10.1134/S1062359013060046

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  • DOI: https://doi.org/10.1134/S1062359013060046

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