Abstract
The individual differences in the response of male and female rats to repeated exposure to acute hypobaric hypoxia were experimentally studied. The time of attitudinal reflex maintenance and recovery in a rotating decompression chamber as well as the value of hypoxic hypothermia after decompression to a simulated altitude of 11200 m were used to evaluate the tolerance to hypoxia. Males demonstrated a slightly higher reactivity than females. At the same time, a more efficient adaptation to hypoxia conserved the body’s compensatory capacity and rapidly restored the functions affected by repeated exposure to the extreme factor. Such long-term adaptation was observed in initially low-resistant females, which could increase their resistance to repeated exposures to the stress factor.
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Original Russian Text © A.S. Shtemberg, Yu.V. Farber, 2006, published in Izvestiya Akademii Nauk, Seriya Biologicheskaya, 2006, No. 6, pp. 725–730.
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Shtemberg, A.S., Farber, Y.V. Sex-related patterns of body tolerance to repeated acute hypobaric hypoxia. Biol Bull Russ Acad Sci 33, 592–596 (2006). https://doi.org/10.1134/S1062359006060100
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DOI: https://doi.org/10.1134/S1062359006060100