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Application of Atmospheric Pressure Photoionization to the Determination of 1,1-Dimethylhydrazine Transformation Products by Liquid Chromatography/Mass Spectrometry

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Abstract

The behavior of eight nitrogen-containing toxic products of rocket fuel transformation (formaldehyde dimethylhydrazone, N,N-dimethylformamide, N,N-dimethylguanidine, 1,2,4-triazole, pyridine, imidazole, pyrazine, pyrazole) under conditions of dopant-free atmospheric pressure photoionization was studied. It was found that the analytes under study give intense signals of protonated molecules, while the efficiency of ionization largely depends on temperature, as well as on the solvent composition and flow rate. Based on a combination of atmospheric pressure photoionization with chromatographic separation on porous graphitized carbon, we proposed a new approach to the highly sensitive determination of rocket fuel transformation products. The developed approach is distinguished by minimal matrix interferences and was successfully tested in the analysis of real samples.

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ACKNOWLEDGMENTS

This work was performed using instrumentation of the “Arktika” Core Facility Center of the Northern (Arctic) Federal University.

Funding

This work was supported by Russian Foundation for Basic Research, project no. 18-29-06018-mk) and a grant of the President of the Russian Federation no. MK-4734.2018.3.

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Authors and Affiliations

  1. Core Facility Center “Arktika,” Lomonosov Northern (Arctic) Federal University, 163002, Arkhangelsk, Russia

    M. S. Popov, N. V. Ul’yanovskii & D. S. Kosyakov

Authors
  1. M. S. Popov
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  2. N. V. Ul’yanovskii
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  3. D. S. Kosyakov
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Corresponding author

Correspondence to N. V. Ul’yanovskii.

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The authors declare no conflict of interest.

ADDITIONAL INFORMATION

N.V. Ulyanovskii: ORCID ID 0000-0003-4796-9313

D.S. Kosyakov: ORCID ID 0000-0001-5223-6857

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Translated by E. Rykova

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Popov, M.S., Ul’yanovskii, N.V. & Kosyakov, D.S. Application of Atmospheric Pressure Photoionization to the Determination of 1,1-Dimethylhydrazine Transformation Products by Liquid Chromatography/Mass Spectrometry. J Anal Chem 75, 1700–1707 (2020). https://doi.org/10.1134/S1061934820130109

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  • DOI: https://doi.org/10.1134/S1061934820130109

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