Journal of Analytical Chemistry

, Volume 74, Issue 1, pp 41–57 | Cite as

Optical Sensors on the Basis of a Polyelectrolyte Peroxidase–Chitosan Complex for the Determination of Biologically Active Compounds

  • I. A. VeselovaEmail author
  • T. N. Shekhovtsova


The review summarizes authors’ works of the last 15 year covering the possibilities, advantages, and prospects for the use of optical sensors based on peroxidase for the determination of a wide range of biologically active compounds, i.e., phenolic compounds and hydroperoxides of different structures, phenothiazines, catecholamines, and their metabolites, for the quality control of drugs, foodstuffs, biomedical research, and clinical diagnostics.


optical sensors horseradish peroxidase indicator reactions spectrophotometry fluorescence phenolic compounds hydroperoxides phenothiazine catecholamines and their metabolites analysis drugs foodstuff biological fluids 



We are grateful to A.V. Kireiko, P.V. Rodionov, and L.I. Malinina for participation in the problem formulation, performance of experiments, and discussion of the results of studies.

This work was supported by the Russian Science Foundation, project no. 14-23-00012.


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© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  1. 1.Department of Chemistry, Moscow State UniversityMoscowRussia

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