Advertisement

Journal of Analytical Chemistry

, Volume 73, Issue 4, pp 317–324 | Cite as

Methods of Determination of Antibiotic Residues in Honey

  • S. M. JakšićEmail author
  • R. D. Ratajac
  • N. B. Prica
  • J. B. Apić
  • D. B. Ljubojević
  • M. Z. Žekić Stošić
  • M. M. Živkov Baloš
Reviews

Abstract

Monitoring antibiotics residues in honey and honey products helps to assess the potential risk of these products to human health. These data provide an insight in the extent of antibiotic treatment that has been used during the beekeeping and enable the evaluation of potential environment pollution with antibiotic residues. This article offers an overview of methods for identification and determination of different antibiotics potentially present in honey, as well as of maximum residue limits for antibiotics in bee products, in particular honey. It is important to stress the importance of strict monitoring system and validation of analytical methods that will enable an accurate, precise and reliable determination of acceptable minimal concentrations of pollutants in honey.

Keywords

antibiotics honey analysis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Al-Waili, N., Salom, K., Al-Ghamdi, A., and Ansari, M.J., Sci. World J., 2012, 930849.Google Scholar
  2. 2.
    Chen, L., Mehta, A., Berenbaum, M., Zangerl, A.R., and Engeseth, N.J., J. Agric. Food Chem., 2000, vol. 48, no. 10, p. 4997.CrossRefGoogle Scholar
  3. 3.
    Mundo, M.A., Padilla-Zakour, O.I., and Worobo, R.W., Int. J. Food Microbiol., 2004, vol. 97, no. 1, p.1.CrossRefGoogle Scholar
  4. 4.
    Kelly, S., Heaton, K., and Hoogewerff, J., Trends Food Sci. Technol., 2005, vol. 16, no. 12, p.555.CrossRefGoogle Scholar
  5. 5.
    Prica, N., Živkov-Baloš, M., Jakšic, S., Mihaljev, Ž., Kartalovic, B., Babic, J., and Savic, S., Arch. Vet. Med., 2014, vol. 7, no. 2, p.99.Google Scholar
  6. 6.
    Bogdanov, S., Apidologie, 2006, vol. 37, no. 1, p.1.CrossRefGoogle Scholar
  7. 7.
    Alippi, A.M., López, A.C., Reynaldi, F.J., Grasso, D.H., and Aguilar, O.M., Vet. Microbiol., 2007, vol. 125, nos. 3–4, p.290.CrossRefGoogle Scholar
  8. 8.
    Reybroeck, W., Ooghe, S., Brabander, H.D., and Daeseleire, E., J. Agric. Food Chem., 2007, vol. 55, no. 21, p. 8359.CrossRefGoogle Scholar
  9. 9.
    Bogdanov, S., Apiacta, 2003, vol. 38, p.190.Google Scholar
  10. 10.
    Wangfuengkanagul, N., Siangproh, W., and Chailapakul, O., Talanta, 2004, vol. 64, no. 5, p. 1183.CrossRefGoogle Scholar
  11. 11.
    World Health Organization. Antimicrobial resistance: No action today, no cure tomorrow. http://www. who.int/world-health-day/2011/en/index.html. Accessed September 7, 2017.Google Scholar
  12. 12.
    European Commission, Council Regulation 2377/90, Off. J. Eur. Commun., 1990, L224.Google Scholar
  13. 13.
    European Commission, Council Regulation 470/2009, Off. J. Eur. Commun., 2009, L151.Google Scholar
  14. 14.
    European Commission, Commission Regulation 37/2010, Off. J. Eur. Commun., 2010, L15.Google Scholar
  15. 15.
    Gunes, M.E., Gunes, N., and Cibik, R., Bulg. J. Agric. Sci., 2009, vol. 15, no. 2, p.163.Google Scholar
  16. 16.
    European Commission, Commission Decision amending Decision 2002/657/EC, Off. J. Eur. Commun., 2003, L71.Google Scholar
  17. 17.
    Code of Federal Regulations, Title 21: Food and Drugs, PART 556—Tolerances for residues of new animal drugs in food. www.ecfr.gov/cgi-bin/retrieveECFR? gp=1&SID=fedfe8b9e21875e35e8462a41527a1-f3&ty =HTML&h=L&r=PART&n=21y6.0.1.1.17#se21.6.55 6_1720. Accessed September 7, 2017.Google Scholar
  18. 18.
    Peres, G.T., Rath, S., and Reyes Reyes, F.G., Food Control, 2010, vol. 21, p.620.CrossRefGoogle Scholar
  19. 19.
    Jeon, M. and Paeng, I.R., Anal. Chim. Acta, 2008, vol. 626, p.180.CrossRefGoogle Scholar
  20. 20.
    Johnson, S. and Jadon, N., Antibiotic Residues in Honey, Centre for Science and Environmentindia Habitat, New Delhi, 2010. http://www.cseindia.org/userfiles/ Antiboitics_Honey.pdf. Accessed September 7, 2017.Google Scholar
  21. 21.
    Codex Alimentarius Commission (2001). Revised Codex Standard for Honey, Codex STAN 12-1981, Rev. 1 (1987), Rev. 2 (2001).Google Scholar
  22. 22.
    Salter, B., Apiacta, 2003, vol. 38, p.198.Google Scholar
  23. 23.
    Heering, W., Usleber, E., Dietrich, R., and Märtlbauer, E., Analyst, 1998, vol. 123, no. 12, p. 2759.CrossRefGoogle Scholar
  24. 24.
    Kaufmann, A., Roth, S., Ryser, B., and Widmer, M., J. AOAC Int., 2001, vol. 85, p.853.Google Scholar
  25. 25.
    Barganska, Z., Namiesnik, J., and Slebioda, M., TrAC, Trends Anal. Chem., 2011, vol. 30, no. 7, p. 1035.CrossRefGoogle Scholar
  26. 26.
    Mulalic, J., Kozacinski, L., Benussi Skukan, A., Filipovic, I., and Runje, M., Meso, 2006, vol. 8, no. 1, p.37.Google Scholar
  27. 27.
    R-Biopharm, Germany. www.r-biopharm.com. Accessed September 7, 2017.Google Scholar
  28. 28.
    Onal, A., Food Chem., 2011, vol. 127, p.197.CrossRefGoogle Scholar
  29. 29.
    Udalova, A.Y., Dmitrienko, S.G., and Apyari, V.V., J. Anal. Chem., 2015, vol. 70, p.577.Google Scholar
  30. 30.
    Rissato, S.R., Galhiane, M.S., de Almeida, M.V., Gerenutti, M., and Apon, B.M., Food Chem., 2007, vol. 101, no. 4, p. 1719.CrossRefGoogle Scholar
  31. 31.
    Anastassiades, M., Lehotay, S.J., Stajnbaher, D., and Schenck, F.J., J. AOAC Int., 2003, vol. 86, no. 2, p.412.Google Scholar
  32. 32.
    Alfredsson, G., Branzell, C., Granelli, K., and Lundstrom, A., Anal. Chim. Acta, 2005, vol. 529, p.47.CrossRefGoogle Scholar
  33. 33.
    Peters, R.J.B., Stolker, A.A.M., Mol, J.G.J., Lommen, A., Lyris, E., Angelis, Y., Vonaparti, A., Stamou, M., Georgakopoulos, C., and Nielen, M.W.F., TrAC, Trends Anal. Chem., 2010, vol. 29, no. 11, p. 1250.CrossRefGoogle Scholar
  34. 34.
    Pena, A., Pelantova, N., Lino, C.M., Silveira, M.I.N., and Solich, P., J. Agric. Food Chem., 2005, vol. 53, no. 10, p. 3784.CrossRefGoogle Scholar
  35. 35.
    Fujita, K., Ito, H., Ishihara, M., Inukai, S., Tanaka, H., and Taniguchi, M., J. Food Hyg. Soc. Jpn., 2008, vol. 49, no. 3, p.196.CrossRefGoogle Scholar
  36. 36.
    Sporns, P., Kwan, S., and Roth, L.A., J. Food Prot., 1986, vol. 49, p.383.CrossRefGoogle Scholar
  37. 37.
    Martel, A.-C., Zeggane, S., Drajnudel, P., Faucon, J.-P., and Aubert, M., Food Addit. Contam., 2006, vol. 23, no. 3, p.265.CrossRefGoogle Scholar
  38. 38.
    Vinas, P., Balsalobre, N., Lopez-Erroz, C., and Hernandez-Cordoba, M., J. Chromatogr. A, 2004, vol. 1022, p.125.CrossRefGoogle Scholar
  39. 39.
    Hakuta, T., Shinzawa, H., and Ozaki, Y., Anal. Sci., 2009, vol. 25, p. 1149.CrossRefGoogle Scholar
  40. 40.
    Anderson, C.R., Rupp, H.S., and Wu, W.-H., J. Chromatogr. A, 2005, vol. 1075, p.23.CrossRefGoogle Scholar
  41. 41.
    Schwaiger, I. and Schuch, R., Dtsch. Lebensm.-Rundsch., 2000, vol. 96, p.93.Google Scholar
  42. 42.
    Diserens, J.M. and Savoy-Perroud, M.C., Determination of sulfonamide residues in honey, Report of the NRC Nestle Research Center, Switzerland, 2002.Google Scholar
  43. 43.
    Pang, G.F., Cao, Y.Z., Fan, C.L., Zhang, J.J., Li, X.M., Li, Z.Y., and Jia, G.Q., Anal. Bioanal. Chem., 2003, vol. 376, p.534.CrossRefGoogle Scholar
  44. 44.
    Galina, A., Benetti, C., Biancotto, G., Baggio, A., Manzinello, C., Dainese, N., and Muntinelli, F., Apiacta, 2005, vol. 40, p.45.Google Scholar
  45. 45.
    Bernal, J., Nozal, M.J., Jiménez, J.J., Martín, M.T., and Sanz, E., J. Chromatogr. A, 2009, vol. 1216, no. 43, p. 7275.CrossRefGoogle Scholar
  46. 46.
    Bonta, V. Al., Marghitas, L., Dezmirean, D., and Bobis, O., Bull. Univ. Agric. Sci. Vet. Med., Anim. Sci. Biotechnol., 2009, vol. 66, nos. 1–2, p.237.Google Scholar
  47. 47.
    Posyniak, A., Sniegocki, T., and Zmudzki, J., Bull. Vet. Inst. Pulawy, 2002, vol. 46, p.111.Google Scholar
  48. 48.
    Posyniak, A., Jazdzewski, K., Pietruszka, K., Mitrowska, K., and Gajda, A., Bull. Vet. Inst. Pulawy, 2008, vol. 52, p.87.Google Scholar
  49. 49.
    Zotou, A. and Vasiliadou, C., Chromatographia, 2006, vol. 64, p.307.CrossRefGoogle Scholar
  50. 50.
    Tsai, W.H., Chuang, H.Y., Chen, H.H., Wu, Y.W., Cheng, S.H., and Huang, T.C., J. Chromatogr. A, 2010, vol. 1217, p. 7812.CrossRefGoogle Scholar
  51. 51.
    Shen, H. and Jiang, H., Anal. Chim. Acta, 2005, vol. 535, p.33.CrossRefGoogle Scholar
  52. 52.
    Pan, C., Zhang, H., Chen, S., Xu, Y., and Jiang, S., Acta Chromatogr., 2006, vol. 17, p.320.Google Scholar
  53. 53.
    Klementz, D. and Pestemer, W., Nachrichtenbl. Dtsch. Pflanzenschutzdienstes (Braunschweig, Ger.), 1996, vol. 48, p.280.Google Scholar
  54. 54.
    Edder, P., Cominoli, A., and Corvi, C., Mitt. Geb. Lebensmittelunters. Hyg., 1998, vol. 89, p.369.Google Scholar
  55. 55.
    Edder, P., Cominoli, A., and Corvi, C., J. Chromatogr. A, 1999, vol. 830, p.345.CrossRefGoogle Scholar
  56. 56.
    Viñas, P., Balsalobre, N., and Hernández-Córdoba, M., Talanta, 2007, vol. 72, p.808.CrossRefGoogle Scholar
  57. 57.
    Draiaia, R., Chefrour, A., Dainese, N., Borin, A., Manzinello, C., Gallina, A., and Mutinelli, F., Afr. J. Biotechnol., 2015, vol. 14, no. 14, p. 1242.CrossRefGoogle Scholar
  58. 58.
    Zimmermann, S., Gierschner, K.H., and Vorwohl, G., Dtsch. Lebensm.-Rundsch., 1993, vol. 89, p.341.Google Scholar
  59. 59.
    European Commission, Commission Decision 2002/657/EC implementing Council Directive 96/23/EC, Off. J. Eur. Commun., 2002, L221.Google Scholar
  60. 60.
    Nakazawa, H., Ino, S., Kato, K., Watanabe, T., Ito, Y., and Oka, H., J. Chromatogr. B: Biomed. Sci. Appl., 1999, vol. 732, no. 1, p.55.CrossRefGoogle Scholar
  61. 61.
    Debayle, D., Dessalces, G., and Grenier-Loustalot, M.F., Anal. Bioanal. Chem., 2008, vol. 391, p. 1011.CrossRefGoogle Scholar
  62. 62.
    Hammel, Y.A., Mohamed, R., Gremaud, E., LeBreton, M.H., and Guy, P.A., J. Chromatogr. A, 2008, vol. 1177, p.58.CrossRefGoogle Scholar
  63. 63.
    De Brabander, H.F., Noppe, H., Verheyden, K., Bussche, J.V., Wille, K., Okerman, L., Vanhaecke, L., Reybroeck, W., Ooghe, S., and Croubels, S., J. Chromatogr. A, 2009, vol. 1216, no. 46, p. 7964.CrossRefGoogle Scholar
  64. 64.
    Lehotay, S.J., Mastovska, K., Amirav, A., Fialkov, A.B., Alon, T., Martos, P.A., de Kok, A., and Fernandez-Alba, A.R., TrAC, Trends Anal. Chem., 2008, vol. 27, no. 11, p. 1070.CrossRefGoogle Scholar
  65. 65.
    Kujawski, M.W. and Namiesnik, J., TrAC, Trends Anal. Chem., 2008, vol. 27, p.785.CrossRefGoogle Scholar
  66. 66.
    Martínez-Vidal, J.L., Aguilera-Luiz, M.M., Romero-González, R., and Garrido-Frenich, A., J. Agric. Food Chem., 2009, vol. 57, p. 1760.CrossRefGoogle Scholar
  67. 67.
    Bie, M., Li, R., Chai, T., Dai, S., Zhao, H., Yang, S., and Qiu, J., Adv. Appl. Sci. Res., 2012, vol. 3, no. 1, p.462.Google Scholar
  68. 68.
    Krivohlavek, A., Žuntar, I., Ivešic, M., Mandic Andacic, I., and Šikic, S., Psychiatr. Danubina, 2014, vol. 26, no. 3, p.537.Google Scholar
  69. 69.
    Mokh, S., Jaber, F., Kouzayha, A., Budzinski, H., and Al Iskandarani, M., Am. J. Anal. Chem., 2014, vol. 5, p.982.CrossRefGoogle Scholar
  70. 70.
    Dubreil-Chéneau, E., Pirotais, Y., Verdon, E., and Hurtaud-Pessel, D., J. Chromatogr. A, 2014, vol. 1339, p.128.CrossRefGoogle Scholar
  71. 71.
    Preu, M., Guyot, D., and Petz, M., J. Chromatogr. A, 1998, vol. 818, p. 95.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • S. M. Jakšić
    • 1
    Email author
  • R. D. Ratajac
    • 1
  • N. B. Prica
    • 1
  • J. B. Apić
    • 1
  • D. B. Ljubojević
    • 1
  • M. Z. Žekić Stošić
    • 1
  • M. M. Živkov Baloš
    • 1
  1. 1.Scientific Veterinary Institute “Novi Sad,”Novi SadSerbia

Personalised recommendations