Abstract
A desorption cell for TLC/DART mass spectrometry is developed. An analysis of mixtures of pharmaceutical substances has shown that the proposed approach can improve the sensitivity of the method and achieve the reproducibility of the recorded mass spectra and selected ion chromatograms.
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References
Ebert, B.L., Galili, N., Tamayo, P., Bosco, J., Mak, R., Pretz, J., Tanguturi, S., Ladd-Acosta, C., Stone, R., Golub, T.R., and Raza, A., PLoS Med., 2008, vol. 5, no. 2, p. e35.
Petucci, C., Diffendal, J., Kaufman, D., Mekonnen, B., Terefenko, G., and Musselman, B., Anal. Chem., 2007, vol. 79, no. 13, p. 5064.
Rehakova, J., Rehurkova, I., Ruprich, J., Kalvodova, J., and Matulova, D., Chem. Listy, 2008, vol. 102, p. 777.
Chernetsova, E.S., Abramovich, R.A., and Revel’skii, I.A., Pharm. Chem. J., 2012, vol. 45, no. 11, p. 598.
Kim, H.J., Jee, E.H., Ahn, K.S., Choi, H.S., and Jang, Y.P., Arch. Pharmacal Res., 2010, vol. 33, no. 9, p. 1355.
Kim, H.J., Oh, M.S., Hong, J., and Jang, Y.P., Phytochem. Anal., 2011, vol. 22, no. 3, p. 258.
Smith, N.J., Domin, M.A., and Scott, L.T., Org. Lett., 2008, vol. 10, no. 16, p. 3493.
Wood, J.L. and Steiner, R.R., Drug Test. Anal., 2011, vol. 3, no. 6, p. 345.
Morlock, G. and Schwack, W., Anal. Bioanal. Chem., 2006, vol. 385, p. 586.
Hea, X.N., Xiea, Z.Q., Gaoa, Y., Hua, W., Guoa, L.B., Jiangc, L., and Lua, Y.F., Spectrochim. Acta, Part B, 2012, vol. 67, p. 64.
Howlett, S.E. and Steiner, R.R., J. Forensic Sci., 2011, vol. 56, no. 5, p. 1261.
Chernetsova, E.S., Revelsky, A.I., and Morlock, G.E., Rapid Commun. Mass Spectrom., 2011, vol. 25, p. 2275.
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Original Russian Text © M.V. Ovcharov, S.S. Barsegyan, S.A. Kovaleva, L.N. Kulikova, R.S. Borisov, 2017, published in Mass-spektrometriya, 2017, Vol. 14, No. 1, pp. 28–32.
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Ovcharov, M.V., Barsegyan, S.S., Kovaleva, S.A. et al. New Approaches to the Application of DART Mass Spectrometry Coupled with Planar Chromatography for the Analysis of Mixtures of Organic Compounds. J Anal Chem 72, 1446–1450 (2017). https://doi.org/10.1134/S106193481714009X
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DOI: https://doi.org/10.1134/S106193481714009X