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Evaluation of 1,10-phenanthroline-5,6-dione as redox mediator for glucose oxidase

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Abstract

A low-cost and simply fabricated amperometric glucose biosensor based on glucose oxidase (GOx) and 1,10-phenanthroline-5,6-dione (PD) modified graphite rod electrode was developed. The electrode exhibited good electrocatalytic activity with a well-defined hyperbolic dependence of amperometric signal upon glucose concentration in the presence and in the absence of oxygen. The electrode showed a good reproducibility and repeatability with relative standard deviation of less than 3 and 5%, respectively. The interaction of GOx with PD mediator was confirmed by means of UV?Vis absorbance spectroscopy.

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Correspondence to Arunas Ramanavicius.

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Zor, E., Oztekin, Y., Ramanaviciene, A. et al. Evaluation of 1,10-phenanthroline-5,6-dione as redox mediator for glucose oxidase. J Anal Chem 71, 77–81 (2016). https://doi.org/10.1134/S1061934816010044

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  • DOI: https://doi.org/10.1134/S1061934816010044

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