Abstract
Conditions of the simultaneous isolation of various types of zolpidem metabolites from samples of real urine by solid-phase extraction have been optimized. Various derivatives of zolpidem hydroxy- and carboxy-metabolites were obtained; their mass-spectral and gas-chromatographic characteristics have been studied. The results ensure the reliable identification of zolpidem metabolites by gas chromatography-mass spectrometry for chemical toxicological and forensic investigations.
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Original Russian Text © E.A. Krylova, S.S. Kataev, Yu.A. Khomov, 2013, published in Zhurnal Analiticheskoi Khimii, 2013, Vol. 68, No. 8, pp. 793–801.
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Krylova, E.A., Kataev, S.S. & Khomov, Y.A. Determination of zolpidem and its metabolites by chromatography-mass spectrometry. J Anal Chem 68, 722–729 (2013). https://doi.org/10.1134/S1061934813080066
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DOI: https://doi.org/10.1134/S1061934813080066