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Journal of Analytical Chemistry

, Volume 66, Issue 14, pp 1470–1473 | Cite as

Real-time monitoring of intravenous hypnotics propofol

  • A. Yu. ElizarovEmail author
  • T. D. Ershov
  • A. V. Kozlovskii
  • A. I. Levshankov
Articles

Abstract

A method for the determination of intravenous hypnotics in blood by monitoring of its concentration in exhaled air under clinical conditions is described. The results of propofol quantification in exhaled air are compared with those in blood collected by means of mass spectrometry. The possibility of the on-line noninvasive control of propofol in blood in the course of complex anesthesia using a mass spectrometer with electron ionization is demonstrated.

Keywords

intravenous anesthesia propofol mass spectrometry concentration 

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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • A. Yu. Elizarov
    • 1
    Email author
  • T. D. Ershov
    • 1
  • A. V. Kozlovskii
    • 2
  • A. I. Levshankov
    • 3
  1. 1.Ioffe Physical Technical InstituteRussian Academy of SciencesSt. PetersburgRussia
  2. 2.ZAO MettekSt. PetersburgRussia
  3. 3.Kirov Military Medical AcademySt. PetersburgRussia

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