Journal of Analytical Chemistry

, Volume 65, Issue 6, pp 588–595 | Cite as

Determination of vitamins in mixtures of various composition by spectrophotometry with self-modeling curve resolution

  • Yu. B. Monakhova
  • S. P. Mushtakova
  • S. S. Kolesnikova


A simple and reliable method for the analysis of mixtures of water- and fat-soluble vitamins in the UV spectral region has been developed using the chemometrical algorithm of self-modeling curve resolution for the decomposition of the spectra of mixtures. The influence of various factors on the result of spectra decomposition has been investigated. The proposed method has been applied to the analysis of model vitamin mixtures as well as multivitamin preparations and energetic drinks.


Standard Reference Mate Additivity Principle Vitamin Mixture Absorbance Difference Experimental Absorption Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Blanco, D., Fernandez, M., and Gutierrez, M., Analyst, 2000, vol. 125, p. 427.CrossRefGoogle Scholar
  2. 2.
    Rocha, F., Filho, O., and Reis, B., Talanta, 2003, vol. 59, p. 191.CrossRefGoogle Scholar
  3. 3.
    Feng, F., Wang, K., Chen, Z., Chen, Q., Lin, J., and Huang, S., Anal. Chim. Acta, 2004, vol. 527, p. 187.CrossRefGoogle Scholar
  4. 4.
    Hernandez, S.R., Ribero, G.G., and Goicoechea, H.C., Talanta, 2003, vol. 61, p. 743.CrossRefGoogle Scholar
  5. 5.
    Morelly, B., J. Pharm. Sci., 1995, vol. 84, p. 34.CrossRefGoogle Scholar
  6. 6.
    Li, L.-S., Da, S.-L., Feng, Y.-Q., and Liu, M., Talanta, 2004, vol. 64, p. 373.CrossRefGoogle Scholar
  7. 7.
    Karpiska, J., Talanta, 2004, vol. 64, p. 801.CrossRefGoogle Scholar
  8. 8.
    Cho, C.M., Ko, J.H., and Cheong, W.J., Talanta, 2000, vol. 51, p. 799.CrossRefGoogle Scholar
  9. 9.
    Kienen, V., Costa, W., Visentainer, J., Souza, N., and Oliveira, C., Talanta, 2008, vol. 75, p. 141.CrossRefGoogle Scholar
  10. 10.
    Hu, Q., Zhou, T., Zhang, L., Li, H., and Fang, Y., Anal. Chim. Acta, 2001, vol. 437, p. 123.CrossRefGoogle Scholar
  11. 11.
    Monferrerpons, L., Capella-peiro, M., Agust, M., and Esteve-Romero, J., J. Chromatogr. A, 2003, vol. 984, p. 223.CrossRefGoogle Scholar
  12. 12.
    Sennello, L.T. and Argoudelis, C.J., Anal. Chem., 1969, vol. 41, p. 171.CrossRefGoogle Scholar
  13. 13.
    Klejdus, B., Petrlova, J., Potesil, D., Vojtech, A., Mikelova, R., Vacek, J., Kizek, R., and Kuban, V., Anal. Chim. Acta, 2004, vol. 520, p. 57.CrossRefGoogle Scholar
  14. 14.
    Hopke, P.K., Anal. Chim. Acta, 2003, vol. 500, p. 365.CrossRefGoogle Scholar
  15. 15.
    Lavine, B. and Workman, J.J., Anal. Chem., 2004, vol. 76, p. 3365.CrossRefGoogle Scholar
  16. 16.
    Monakhova, Yu.B., Astakhov, S.A., and Mushtakova, S.P., Zhurn. anal. khim., 2009, vol. 64, no. 5, p. 495 [J. Anal. Chem. (Engl. Transl.), vol. 64, no. 5, p. 479].Google Scholar
  17. 17.
    Stogbauer, H., Kraskov, A., Astakhov, S.A., and Grassberger, P., Phys. Rev., E, 2004, vol. 70, no. 066123.Google Scholar
  18. 18.
    Kraskov, A., Stogbauer, H., and Grassberger, P., Phys. Rev. E, 2004, vol. 69, no. 066138.Google Scholar
  19. 19.
    Astakhov, S., Stogbauer, H., Kraskov, A., and Grassberger, P., Electronnyi resurs (Electronic Resource),
  20. 20.
    Windig, W. and Guilment, J., Anal. Chem., 1991, vol. 63, p. 1425.CrossRefGoogle Scholar
  21. 21.
    Widjaja, E., Li, C., Chew, W., and Garland, M., Anal. Chem., 2003, vol. 75, p. 4499.CrossRefGoogle Scholar
  22. 22.
    Bu, D.S. and Brown, C.W., Appl. Spectrosc., 2000, vol. 54, p. 1214.CrossRefGoogle Scholar
  23. 23.
    Learned-Miller, E.G. and Fisher, J.W., J. Mach. Learn. Res., 2003, vol. 4, p. 1271.CrossRefGoogle Scholar
  24. 24.
    Nuzillard, D., Bourg, S., and Nuzillard, J., J. Magn. Reson., 1998, vol. 133, p. 358.CrossRefGoogle Scholar
  25. 25.
    Varmuza, K., Karlovits, M., and Demuth, W., Anal. Chim. Acta, 2003, vol. 490, p. 313.CrossRefGoogle Scholar
  26. 26.
    Vershinin, V.I., Derendyaev, B.D., and Lebedev, K.S., Komp’yuternaya identifikatsiya organicheskikh soedinenii (Computer-Assisted Identification of Organic Compounds), Moscow: Akademkniga, 2002.Google Scholar
  27. 27.
    Milman, B., Trends Anal. Chem., 2005, vol. 24, p. 493.CrossRefGoogle Scholar
  28. 28.
    Grant, D.C. and Helleur, R.J., Anal. Bioanal. Chem., 2008, vol. 391, p. 2811.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2010

Authors and Affiliations

  • Yu. B. Monakhova
    • 1
  • S. P. Mushtakova
    • 1
  • S. S. Kolesnikova
    • 1
  1. 1.Institute of ChemistrySaratov State UniversitySaratovRussia

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