Abstract
Highly sensitive piezoelectric quartz immunosensors are proposed for the rapid selective determination of chloroacetanilide herbicides. Receptor coatings are hapten-protein conjugates immobilized on the presilanized surface of sensor silver or gold electrodes. Complementary pairs of immunoreagents ensuring the maximum analytical signal are selected on the basis of affinity constants found by the Sketchard method. The detection limits for acetochlor and alachlor are 0.02 ng/mL and that for butachlor is 0.002 ng/mL. Sensors were used to determine residual amounts of herbicides in foodstuffs and environmental objects.
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Rodriguez, R., Manes, J., and Pico, Y., Anal. Chim. Acta, 2003, vol. 75, p. 452.
Pico, Y., Rodrguez, R., and Manes, J., Trends Anal. Chem., 2003, vol. 22, no. 3, p. 133.
Rodrguez, R., Pico, Y., Font, G., and Manes, J., J. Chromatogr., 2002, vol. 949, nos. 1–2, p. 359.
EPA-738-F-98-018, 1998.
Yakovleva, J.N., Zherdev, A.V., Popova, V.A., Eremin, S.A., and Dzantiev, B.B., Anal.Chim. Acta, 2003, vol. 491, no. 1, p. 1.
Hawkins, P.R., Novic, S., Cox, P., Neilan, B.A., Burns, B.P., Shaw, G., Wickramasinghe, W., Peerapornpisal, Yu., Ruangyuttikarn, W., Itayama, T., Saitou, T., Mizuochi, M., and Inamori, Yu., J. Water Suppl. Res. Technol., 2005, vol. 54, p. 509.
Deryabina, M.A., Yakovleva, Yu.N., Popova, V.A., and Eremin, S.A., Zh. anal. khim., 2005, vol. 60, no. 1, p. 91 [J. Anal. Chem. (Engl. Transl.), vol. 60, no. 1, p. 80].
Kim, N. and Park, I.-S., Biosens. Bioelectron., 2003, vol. 18, no. 9, p. 1101.
Lima, J.L.F., Delerut-Matos, C., and Vas, C.V.F., Analyst, 2000, vol. 125, no. 7, p. 1281.
Su, X., Chew, F.T., and Li, S., Biosens. Bioelectron., 2000, vol. 15, nos. 11–12, p. 629.
Lebedev, M.Yu., Eremin, S.A., and Skladal, P., Anal. Lett., 2003, vol. 36, no. 11, p. 2443.
Nartova, Yu.V., Ermolaeva, T.N., and Eremin, S.A., Sorbts. khromatogr. protsessy, 2006, vol. 1, no. 5, p. 764.
Ermolaeva, T.N., Dergunova, E.S., Kalmykova, E.N., and Eremin, S.A., Zh. anal. khim., 2006, vol. 61, no. 6, p. 660 [J. Anal. Chem. (Engl. Transl.), vol. 61, no. 6, p. 609].
Melikhova, E.V., Cand. Sci. (Chem.) Dissertation, Voronezh: Voronezh State Univ., 2006.
Buck, R.P., Lindner, E., Kutner, W., and Inzelt, G., Pure Appl. Chem., 2004, vol. 76, no. 6, p. 1139.
Crooks, S., McCarney, B., Traynor, I.M., Thompson, C.S., Floyd, S., and Elliott, C.T., Anal. Chim. Acta, 2003, vol. 483, nos. 1–2, p. 181.
Il’icheva, N.Yu., Beilinson, R.M., Medyantseva, E.P., Budnikov, G.K., and Vanyagina, O.N., Vestn. Mosk. Univ., 2002, vol. 43, no. 6, p. 409.
Vorob’eva, L.A., Khimicheskii analiz pochv (Chemical Analysis of Soils), Moscow: Mosk. Gos. Univ., 1998.
Kalmykova, E.N., Melikhova, E.V., Dergunova, E.S., Eremin, S.A., and Ermolaeva, T.N., Sorbts. khromatogr. protsessy, 2004, vol. 4, no. 5, p. 597.
GN (Hygienic Regulations) 1.2.1323-03: Hygienic Norms on the Content of Pesticides in the Environmental Objects, 2003.
Belobordov, V.L., Zurabyan, S.E., Luzin, A.P., and Tyukavkina, N.A., Organicheskaya khimiya (Organic Chemistry), Tyukavkina, N.A., Ed., Moscow: Drofa, 2002, vol. 1.
Analytical Chemistry, Kellner, R., Mermet, J.-M., Otto, M., and Vidmer, G.M., Eds., Weinheim: Wiley, 1998.
Ren, X., Kobatake, E., and Aizawa, M., Analist, 2000, vol. 125, no. 4, p. 669.
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Original Russian Text © Yu.V. Nartova, S.A. Eremin, T.N. Ermolaeva, 2008, published in Zhurnal Analiticheskoi Khimii, 2008, Vol. 63, No. 12, pp. 1302–1310.
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Nartova, Y.V., Eremin, S.A. & Ermolaeva, T.N. Mass-sensitive immunosensors for determining chloroacetanilide herbicides. J Anal Chem 63, 1191–1198 (2008). https://doi.org/10.1134/S1061934808120095
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DOI: https://doi.org/10.1134/S1061934808120095